Fisetin improves glucose homeostasis through the inhibition of gluconeogenic enzymes in hepatic tissues of streptozotocin induced diabetic rats

GS Prasath, SI Pillai, SP Subramanian - European journal of pharmacology, 2014 - Elsevier
Liver plays a vital role in blood glucose homeostasis. Recent studies have provided
considerable evidence that hepatic glucose production (HGP) plays an important role in the …

Modulatory effects of fisetin, a bioflavonoid, on hyperglycemia by attenuating the key enzymes of carbohydrate metabolism in hepatic and renal tissues in …

GS Prasath, SP Subramanian - European journal of pharmacology, 2011 - Elsevier
Fisetin (3, 7, 3′, 4′-tetrahydroxyflavone) is a bioflavonoid found in fruits and vegetables. It
exhibits a wide variety of pharmacological properties, including antioxidant, antiinflammatory …

Antihyperglycemic effect of fraxetin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats

R Murali, S Srinivasan, N Ashokkumar - Biochimie, 2013 - Elsevier
Epidemiological studies have demonstrated that the diabetes mellitus is a serious health
burden for both governments and healthcare providers. The present study was hypothesized …

Grapefruit juice improves glucose intolerance in streptozotocin-induced diabetes by suppressing hepatic gluconeogenesis

JA Hayanga, SP Ngubane, AN Murunga… - European journal of …, 2016 - Springer
Purpose Hypoglycemic effects of grapefruit juice (GFJ) are widely recognized, but the
mechanism (s) by which GFJ lowers blood glucose levels have not previously been …

Fisetin averts oxidative stress in pancreatic tissues of streptozotocin-induced diabetic rats

GS Prasath, CS Sundaram, SP Subramanian - Endocrine, 2013 - Springer
Persistent hyperglycemia is associated with chronic oxidative stress which contributes to the
development and progression of diabetes-associated complications. The sensitivity of …

Hesperidin, a citrus flavonoid ameliorates hyperglycemia by regulating key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats

R Sundaram, E Nandhakumar… - Toxicology …, 2019 - Taylor & Francis
The present study investigated the protective effect of hesperidin on carbohydrate
metabolizing enzymes in streptozotocin-induced diabetic rats. Hesperidin was administered …

[HTML][HTML] Fisetin protects against streptozotocin-induced diabetic cardiomyopathy in rats by suppressing fatty acid oxidation and inhibiting protein kinase R

JZ ALTamimi, MN BinMowyna, NA AlFaris… - Saudi Pharmaceutical …, 2021 - Elsevier
This study examined if the Fisetin against streptozotocin-induced diabetic cardiomyopathy
(DC) in rats involves regulating cardiac metabolism and suppressing protein kinase R …

Ferulic acid exerts its antidiabetic effect by modulating insulin-signalling molecules in the liver of high-fat diet and fructose-induced type-2 diabetic adult male rat

A Narasimhan, M Chinnaiyan… - Applied physiology …, 2015 - cdnsciencepub.com
Ferulic acid (FA) is a phenolic phytochemical known for its antidiabetic property The present
study is designed to evaluate the mechanism behind its antidiabetic property in high-fat and …

Anti-diabetic effect of sorghum extract on hepatic gluconeogenesis of streptozotocin-induced diabetic rats

J Kim, Y Park - Nutrition & metabolism, 2012 - Springer
Background It has been suggested that Sorghum, a rich source of phytochemicals, has a
hypoglycemic effect, but the mechanism is unknown. We investigated the effects of oral …

[PDF][PDF] Modulatory effects of naringin on hepatic key enzymes of carbohydrate metabolism in high-fat diet/low-dose streptozotocin-induced diabetes in rats

L Pari, R Chandramohan - Gen Physiol Biophys, 2017 - researchgate.net
We evaluated the modulatory effects of naringin on altered hepatic key enzymes of
carbohydrate metabolism in high-fat diet/low-dose streptozotocin-induced diabetic rats. Oral …