Self-replicating molecules provide a simple approach for investigating fundamental
processes in scenarios of the emergence of life. Although homochirality is an important …

Self‐replication plays a central role in the origin of life and in strategies to synthesize life de
novo. Studies on self‐replication have focused mostly on isolated systems, while the …

Unraveling how chemistry can give rise to biology is one of the greatest challenges of
contemporary science. Achieving life-like properties in chemical systems is therefore a …

The study of the interplay between different self‐replicating molecules constitutes an
important new phase in the synthesis of life and in unravelling the origin of life. Here we …

A formidable synthetic apparatus for the creation of nanoscale molecular structures and
supramolecular assemblies through molecular structures can potentially be created from …

Examples of chemical systems capable of templating and catalysing their own synthesis—
self-replicating systems—have begun to appear in the chemical literature over the last 15 …

A “self-replicator” is usually understood to be an object of definite form that promotes the
conversion of materials in its environment into a nearly identical copy of itself. The challenge …

Minimal self-replicating systems typically consist of three components: a product molecule,
and two substrate molecules that become joined to form another product molecule. An …

Unravelling how the complexity of living systems can (have) emerge (d) from simple
chemical reactions is one of the grand challenges in contemporary science. Evolving …

The use of self-complementary structures in replication experiments is discussed, and a
second generation of self-replicating molecules is introduced. Key design elements of the …