Non-nutritive sweeteners are thought to be useful replacements for caloric sweeteners in
sweet food and beverages, since the reduction in energy and carbohydrate intake may lead …

Background Recently, the absence of metabolic effects from nonnutritive sweeteners has
been questioned. Objective The aim of this study was to evaluate the effects of sucralose …

Background The effect of nonnutritive sweeteners on appetite is controversial. Some studies
have found changes in certain appetite control hormones with sucralose intake that may be …

Background Non-nutritive sweeteners (NNS) are widely consumed by humans due to their
apparent innocuity, especially sucralose. However, several studies link sucralose …

The discovery of gut sweet taste receptors has led to speculations that non-nutritive
sweeteners, including sucralose, may affect glucose control. A double-blind, parallel …

ABSTRACT Background Low-calorie sweeteners (LCSs) provide sweetness with little or no
energy. However, each LCS's unique chemical structure has potential to elicit different …

This study aimed to determine the effect of pure forms of sucralose and aspartame, in doses
reflective of common consumption, on glucose metabolism. Healthy participants consumed …

OBJECTIVE: To investigate the effect of 3-months' daily administration of high doses of
sucralose, a non-nutritive sweetener, on glycemic control in subjects with type 2 diabetes …

Methods: Fasted subjects were studied on 4 study days in random order. Subjects
consumed 50 ml of either water, sucralose (0.083% w/v), a non-sweet, glucose-polymer …

Context: Non-nutritive sweeteners can bind to sweet-taste receptors present not only in the
oral cavity, but also on enteroendocrine and pancreatic islet cells. Thus, these sweeteners …