The tissue-resident skeletal stem cells (SSCs), which are self-renewal and multipotent,
continuously provide cells (including chondrocytes, bone cells, marrow adipocytes, and …

Tissue-resident stem cells are a group of stem cells distinguished by their capacity for self-
renewal and multilineage differentiation capability with tissue specificity. Among these tissue …

Bone-related maladies are a major health burden on modern society. Loss of skeletal
integrity and regeneration capacity through aging, obesity, and disease follows from a …

Abstract Purpose of Review Skeletal stem cells (SSCs) are considered to play important
roles in bone development and repair. These cells have been historically defined by their in …

Skeletal stem cells (SSCs) generate the progenitors needed for growth, maintenance and
repair of the skeleton. Historically, SSCs have been defined as bone marrow-derived cells …

Skeletal stem cells (SSCs) reside in the postnatal bone marrow and give rise to cartilage,
bone, hematopoiesis-supportive stroma and marrow adipocytes in defined in vivo assays …

Skeletal stem and progenitor cell populations are crucial for bone physiology.
Characterization of these cell types remains restricted to heterogenous bulk populations with …

Skeletal stem/progenitor cells (SSPCs), characterized by self-renewal and multipotency, are
essential for skeletal development, bone remodeling, and bone repair. These cells have …

Stem cell regulation and hierarchical organization of human skeletal progenitors remain
largely unexplored. Here, we report the isolation of a self-renewing and multipotent human …

Human skeletal stem cells (SSCs) have been discovered in fetal and adult long bones.
However, the spatiotemporal ontogeny of human embryonic SSCs during early …