One primary objective of synthetic biology is to improve the sustainability of chemical
manufacturing. Naturally occurring biological systems can utilize a variety of carbon sources …

Acinetobacter baylyi ADP1 is a non-pathogenic soil bacterium known for its metabolic
diversity and high natural transformation and recombination efficiency. For these features, A …

For more than 25 years, Acinetobacter baylyi ADP1 has been used in molecular biology
studies that address a broad range of questions. Recently, the rapid accumulation of data …

One goal of synthetic biology is to improve the efficiency and predictability of living cells by
removing extraneous genes from their genomes. We demonstrate improved methods for …

Adaptive laboratory evolution (ALE) is a powerful approach for improving phenotypes of
microbial hosts. Evolved strains typically contain numerous mutations that can be revealed …

Acinetobacter sp. strain ADP1 is a naturally transformable gram-negative bacterium with
simple culture requirements, a prototrophic metabolism and a compact genome of 3.7 Mb …

Acinetobacter baylyi ADP1 has the potential to be a versatile bacterial host for synthetic
biology because it is naturally transformable. To examine the genetic reliability of this …

Expansive knowledge of bacterial metabolism has been gained from genome sequencing
output, but the high proportion of genes lacking a proper functional annotation in a given …

The genomes of most bacteria contain mobile DNA elements that can contribute to
undesirable genetic instability in engineered cells. In particular, transposable insertion …

Information produced by the annotation of an 'average bacterial genome'can be separated
into three parts. One-third represents what we know, another third what we think we know …