ERp57/PDIA3: new insight
S Chichiarelli, F Altieri, G Paglia, E Rubini… - Cellular & Molecular …, 2022 - Springer
The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although
predominantly located in the endoplasmic reticulum (ER), has indeed been found in other …
predominantly located in the endoplasmic reticulum (ER), has indeed been found in other …
[HTML][HTML] The human PDI family: versatility packed into a single fold
C Appenzeller-Herzog, L Ellgaard - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
The enzymes of the protein disulfide isomerase (PDI) family are thiol–disulfide
oxidoreductases of the endoplasmic reticulum (ER). They contain a CXXC active-site …
oxidoreductases of the endoplasmic reticulum (ER). They contain a CXXC active-site …
[HTML][HTML] PDIA4: The basic characteristics, functions and its potential connection with cancer
Disulfide bond formation is catalyzed by the protein disulfide Isomerases (PDI) family. This is
a critical step in protein folding which occurs within the endoplasmic reticulum. PDIA4, as a …
a critical step in protein folding which occurs within the endoplasmic reticulum. PDIA4, as a …
Increased expression of PDIA3 and its association with cancer cell proliferation and poor prognosis in hepatocellular carcinoma
H Takata, M Kudo, T Yamamoto, J Ueda… - Oncology …, 2016 - spandidos-publications.com
The prognosis of hepatocellular carcinoma (HCC) is unfavorable following complete tumor
resection. The aim of the present study was to identify a molecule able to predict HCC …
resection. The aim of the present study was to identify a molecule able to predict HCC …
Pseudogene PDIA3P1 promotes cell proliferation, migration and invasion, and suppresses apoptosis in hepatocellular carcinoma by regulating the p53 pathway
Y Kong, L Zhang, Y Huang, T He, L Zhang, X Zhao… - Cancer Letters, 2017 - Elsevier
Pseudogenes are a subclass of long non-coding (lnc) RNAs that arose from protein-coding
genes, but have lost the ability to produce proteins. Pseudogenes play an important role in …
genes, but have lost the ability to produce proteins. Pseudogenes play an important role in …
Identification of SVIP as an endogenous inhibitor of endoplasmic reticulum-associated degradation
P Ballar, Y Zhong, M Nagahama, M Tagaya… - Journal of Biological …, 2007 - ASBMB
Misfolded proteins in the endoplasmic reticulum (ER) are eliminated by a process known as
ER-associated degradation (ERAD), which starts with misfolded protein recognition …
ER-associated degradation (ERAD), which starts with misfolded protein recognition …
Re-discovering PDE3 inhibitors-new opportunities for a long neglected target
PE Thompson, V Manganiello… - Current topics in …, 2007 - ingentaconnect.com
The PDE3 enzymes or “low Km cGMP-inhibited phosphodiesterases” have long been
established as important mediators of cellular physiology, and synthetic PDE3 inhibitors …
established as important mediators of cellular physiology, and synthetic PDE3 inhibitors …
[HTML][HTML] PDIA3: Structure, functions and its potential role in viral infections
The catalysis of disulphide (single bondSsingle bondSsingle bond) bonds is the most
important characteristic of protein disulphide isomerase (PDI) family. Catalysis occurs in the …
important characteristic of protein disulphide isomerase (PDI) family. Catalysis occurs in the …
Comparison of recombinant human PDE4 isoforms: interaction with substrate and inhibitors
N Saldou, R Obernolte, A Huber, PA Baecker… - Cellular signalling, 1998 - Elsevier
Four cyclic-nucleotide phosphodiesterase (PDE) genes belonging to the PDE4 family
(PDE4A, 4B, 4C and 4D) have been identified. All four isogenes, including several deletions …
(PDE4A, 4B, 4C and 4D) have been identified. All four isogenes, including several deletions …
Structural and functional features in human PDE5A1 regulatory domain that provide for allosteric cGMP binding, dimerization, and regulation
R Zoraghi, EP Bessay, JD Corbin, SH Francis - Journal of Biological …, 2005 - ASBMB
The cGMP-binding cGMP-specific phosphodiesterase (PDE5) contains a catalytic domain
that hydrolyzes cGMP and a regulatory (R) domain that contains two GAFs (a and b; GAF is …
that hydrolyzes cGMP and a regulatory (R) domain that contains two GAFs (a and b; GAF is …