Long-term outcomes of childhood left ventricular noncompaction cardiomyopathy: results from a national population-based study

WY Shi, M Moreno-Betancur, AW Nugent, M Cheung… - Circulation, 2018 - Am Heart Assoc
Background: Long-term outcomes for childhood left ventricular noncompaction (LVNC) are
uncertain. We examined late outcomes for children with LVNC enrolled in a national …

Cardiomyopathy phenotypes and outcomes for children with left ventricular myocardial noncompaction: results from the pediatric cardiomyopathy registry

JL Jefferies, JD Wilkinson, LA Sleeper, SD Colan… - Journal of cardiac …, 2015 - Elsevier
Background Left ventricular noncompaction (LVNC) is a distinct form of cardiomyopathy
characterized by hypertrabeculation of the left ventricle. The LVNC phenotype may occur in …

Reduced systolic function and not genetic variants determine outcome in pediatric and adult left ventricular noncompaction cardiomyopathy

A Schultze-Berndt, J Kühnisch, C Herbst… - Frontiers in …, 2021 - frontiersin.org
Background: Left ventricular noncompaction cardiomyopathy (LVNC CMP) is a genetic
cardiomyopathy. Genotype-phenotype correlation and clinical outcome of genetic variants in …

Medical therapy leads to favorable remodeling in left ventricular non-compaction cardiomyopathy: dilated phenotype

JJ Parent, JA Towbin, JL Jefferies - Pediatric cardiology, 2016 - Springer
Left ventricular non-compaction cardiomyopathy (LVNC) is a distinct and heterogeneous
entity that can lead to progressive cardiac dysfunction and heart failure. LVNC with dilation …

Predictors of adverse outcome in adolescents and adults with isolated left ventricular noncompaction

M Greutmann, ML Mah, CK Silversides… - The American journal of …, 2012 - Elsevier
Isolated left ventricular noncompaction is a rare form of primary cardiomyopathy. Although
increasingly diagnosed, data on the outcomes are limited. To define the predictors of …

Clinical characterization of left ventricular noncompaction in children: a relatively common form of cardiomyopathy

RH Pignatelli, CJ McMahon, WJ Dreyer, SW Denfield… - Circulation, 2003 - Am Heart Assoc
Background—Left ventricular noncompaction (LVNC) is a reportedly uncommon genetic
disorder of endocardial morphogenesis with a reportedly high mortality rate. The purpose of …

Is left ventricular noncompaction in children truly an isolated lesion?

SF Tsai, ES Ebenroth, RA Hurwitz, TM Cordes… - Pediatric …, 2009 - Springer
Left ventricular noncompaction (LVNC) is a form of cardiomyopathy resulting from a disorder
of endomyocardial morphogenesis. It has been associated with significant morbidity and …

Long-Term Prognosis of Different Subtypes of Left Ventricular Noncompaction Cardiomyopathy Patients: A Retrospective Study in China

S Gao, S Zhang, Z Wang, M Wu, C Gu, R Bai… - Journal of …, 2023 - mdpi.com
Left ventricular noncompaction (LVNC) is a heterogeneous cardiomyopathy that can be
classified into different subtypes based on morphologic and functional features. However …

Genetic profile of left ventricular noncompaction cardiomyopathy in children—a single reference center experience

D Piekutowska-Abramczuk, A Paszkowska, E Ciara… - Genes, 2022 - mdpi.com
Background: Left ventricular noncompaction cardiomyopathy (LVNC) is a rare cardiac
disorder characterised by the presence of a two-layer myocardium with prominent …

Genetic testing in pediatric left ventricular noncompaction

EM Miller, RB Hinton, R Czosek, A Lorts… - Circulation …, 2017 - Am Heart Assoc
Background—Left ventricular noncompaction (LVNC) can occur in isolation or can co-occur
with a cardiomyopathy phenotype or cardiovascular malformation. The yield of …