Clinical significance of microbiota changes under the influence of psychotropic drugs. An updated narrative review

A Misera, I Łoniewski, J Palma, M Kulaszyńska… - Frontiers in …, 2023 - frontiersin.org
Relationship between drugs and microbiota is bilateral. Proper composition thus function of
microbiota is a key to some medications used in modern medicine. However, there is also …

Differential effects of psychotropic drugs on microbiome composition and gastrointestinal function

S Cussotto, CR Strain, F Fouhy, RG Strain… - …, 2019 - Springer
Rationale Growing evidence supports a role for the microbiota in regulating gut-brain
interactions and, thus, psychiatric disorders. Despite substantial scientific efforts to delineate …

Unravelling the antimicrobial action of antidepressants on gut commensal microbes

Y Ait Chait, W Mottawea, TA Tompkins, R Hammami - Scientific reports, 2020 - nature.com
Over the past decade, there has been increasing evidence highlighting the implication of the
gut microbiota in a variety of brain disorders such as depression, anxiety, and …

The microbiome in mental health: potential contribution of gut microbiota in disease and pharmacotherapy management

SA Flowers, VL Ellingrod - Pharmacotherapy: The Journal of …, 2015 - Wiley Online Library
The gut microbiome is composed of~ 1013–1014 microbial cells and viruses that exist in a
symbiotic bidirectional communicative relationship with the host. Bacterial functions in the …

[HTML][HTML] Psychotropics and the microbiome: a chamber of secrets…

S Cussotto, G Clarke, TG Dinan, JF Cryan - Psychopharmacology, 2019 - Springer
The human gut contains trillions of symbiotic bacteria that play a key role in programming
different aspects of host physiology in health and disease. Psychotropic medications act on …

Effects of psychotropics on the microbiome in patients with depression and anxiety: considerations in a naturalistic clinical setting

Y Tomizawa, S Kurokawa, D Ishii… - International Journal …, 2021 - academic.oup.com
Background The antibacterial effects of psychotropics may be part of their pharmacological
effects when treating depression. However, limited studies have focused on gut microbiota …

Antidepressants, antimicrobials or both? Gut microbiota dysbiosis in depression and possible implications of the antimicrobial effects of antidepressant drugs for …

D Macedo, AJM Chaves Filho, CNS de Sousa… - Journal of affective …, 2017 - Elsevier
Objectives The first drug repurposed for the treatment of depression was the tuberculostatic
iproniazid. At present, drugs belonging to new classes of antidepressants still have …

Nutritional and therapeutic approaches for protecting human gut microbiota from psychotropic treatments

YA Chait, W Mottawea, TA Tompkins… - Progress in Neuro …, 2021 - Elsevier
Emerging evidence highlighted the essential role played by the microbiota-gut-brain axis in
maintaining human homeostasis, including nutrition, immunity, and metabolism. Much …

[HTML][HTML] Interactions between antidepressants and intestinal microbiota

F Xu, Q Xie, W Kuang, Z Dong - Neurotherapeutics, 2023 - Elsevier
The microbiota-gut-brain axis has been shown to influence human health and diseases,
including depression. The interactions between drugs and intestinal microbiota are complex …

[HTML][HTML] Psycho-pharmacomicrobiomics: a systematic review and meta-analysis

A Minichino, T Preston, JB Fanshawe, P Fusar-Poli… - Biological …, 2023 - Elsevier
Background Understanding the interactions between the gut microbiome and psychotropic
medications (psycho-pharmacomicrobiomics) could improve treatment stratification …