Current approaches and developments in transcript profiling of the human placenta

HEJ Yong, SY Chan - Human reproduction update, 2020 - academic.oup.com
BACKGROUND The placenta is the active interface between mother and foetus, bearing the
molecular marks of rapid development and exposures in utero. The placenta is routinely …

[HTML][HTML] Transcriptome landscape of the human placenta

J Kim, K Zhao, P Jiang, Z Lu, J Wang, JC Murray… - BMC genomics, 2012 - Springer
Background The placenta is a key component in understanding the physiological processes
involved in pregnancy. Characterizing genes critical for placental function can serve as a …

Revealing the molecular landscape of human placenta: a systematic review and meta-analysis of single-cell RNA sequencing studies

E Derisoud, H Jiang, A Zhao… - Human …, 2024 - academic.oup.com
BACKGROUND With increasing significance of developmental programming effects
associated with placental dysfunction, more investigations are devoted to improving the …

Placental transcriptome in development and pathology: expression, function, and methods of analysis

B Cox, K Leavey, U Nosi, F Wong, J Kingdom - American journal of …, 2015 - Elsevier
The placenta is the essential organ of mammalian pregnancy and errors in its development
and function are associated with a wide range of human pathologies of pregnancy. Genome …

Considerations when processing and interpreting genomics data of the placenta

C Konwar, G Del Gobbo, V Yuan, WP Robinson - Placenta, 2019 - Elsevier
The application of genomic approaches to placental research has opened exciting new
avenues to help us understand basic biological properties of the placenta, improve prenatal …

A comprehensive analysis of the human placenta transcriptome

J Saben, Y Zhong, S McKelvey, NK Dajani, A Andres… - Placenta, 2014 - Elsevier
As the conduit for nutrients and growth signals, the placenta is critical to establishing an
environment sufficient for fetal growth and development. To better understand the …

[HTML][HTML] Whole-transcriptome analysis delineates the human placenta gene network and its associations with fetal growth

MA Deyssenroth, S Peng, K Hao, L Lambertini… - BMC genomics, 2017 - Springer
Background The placenta is the principal organ regulating intrauterine growth and
development, performing critical functions on behalf of the developing fetus. The delineation …

Comparative transcriptomic analysis of human placentae at term and preterm delivery

AG Paquette, HM Brockway, ND Price… - Biology of …, 2018 - academic.oup.com
Preterm birth affects 1 out of every 10 infants in the United States, resulting in substantial
neonatal morbidity and mortality. Currently, there are few predictive markers and few …

[HTML][HTML] Single cell transcriptome research in human placenta

H Li, Q Huang, Y Liu, LX Garmire - Reproduction, 2020 - rep.bioscientifica.com
Human placenta is a complex and heterogeneous organ interfacing between the mother
and the fetus that supports fetal development. Alterations to placental structural components …

[HTML][HTML] Mid-gestational gene expression profile in placenta and link to pregnancy complications

L Uusküla, J Männik, K Rull, A Minajeva, S Koks… - PLoS …, 2012 - journals.plos.org
Despite the importance of placenta in mediating rapid physiological changes in pregnancy,
data on temporal dynamics of placental gene expression are limited. We completed the first …