Synthesis of some novel hydrazone and 2-pyrazoline derivatives: Monoamine oxidase inhibitory activities and docking studies
B Evranos-Aksöz, S Yabanoğlu-Çiftçi, G Uçar… - Bioorganic & medicinal …, 2014 - Elsevier
A novel series of 2-pyrazoline and hydrazone derivatives were synthesized and investigated
for their human monoamine oxidase (hMAO) inhibitory activity. All compounds inhibited the …
for their human monoamine oxidase (hMAO) inhibitory activity. All compounds inhibited the …
Synthesis and screening of human monoamine oxidase‐A inhibitor effect of new 2‐pyrazoline and hydrazone derivatives
B Evranos‐Aksöz, İ Baysal… - Archiv der …, 2015 - Wiley Online Library
A group of 3, 5‐diaryl‐2‐pyrazoline and hydrazone derivatives was prepared via the
reaction of various chalcones with hydrazide compounds in ethanol. Twenty original …
reaction of various chalcones with hydrazide compounds in ethanol. Twenty original …
New 2-pyrazoline and hydrazone derivatives as potent and selective monoamine oxidase A inhibitors
Thirty compounds having 1-[2-(5-substituted-2-benzoxazolinone-3-yl) acetyl]-3, 5-
disubstitutedphenyl-2-pyrazoline structure and nine compounds having N′-(1, 3 …
disubstitutedphenyl-2-pyrazoline structure and nine compounds having N′-(1, 3 …
Design, Synthesis and Biological Evaluation of Novel N-Pyridyl-Hydrazone Derivatives as Potential Monoamine Oxidase (MAO) Inhibitors
A new series of N-pyridyl-hydrazone derivatives was synthesized by using a simple and
efficient method. The final compounds obtained were screened for their inhibitory potency …
efficient method. The final compounds obtained were screened for their inhibitory potency …
Synthesis of new hydrazone derivatives and evaluation of their monoamine oxidase inhibitory activity
A novel series of hydrazone derivatives were designed and synthesized. Their structures
were characterized by IR, 1 H NMR, 13 C NMR and HR-MS spectroscopic methods. The …
were characterized by IR, 1 H NMR, 13 C NMR and HR-MS spectroscopic methods. The …
Towards development of selective and reversible pyrazoline based MAO-inhibitors: Synthesis, biological evaluation and docking studies
Ten novel 3, 5-diaryl pyrazolines were synthesized and investigated for their monoamine
oxidase (MAO) inhibitory property. All the molecules were found to be reversible and …
oxidase (MAO) inhibitory property. All the molecules were found to be reversible and …
Design, synthesis, in vitro and in silico evaluation of new pyrrole derivatives as monoamine oxidase inhibitors
In an effort to develop potent monoamine oxidase (MAO) inhibitors, new pyrrole derivatives
were obtained via the selective reduction of the C C bonds of 1‐(1‐methyl‐1H‐pyrrol‐2‐yl) …
were obtained via the selective reduction of the C C bonds of 1‐(1‐methyl‐1H‐pyrrol‐2‐yl) …
Selective inhibitory activity against MAO and molecular modeling studies of 2-thiazolylhydrazone derivatives
F Chimenti, E Maccioni, D Secci… - Journal of medicinal …, 2007 - ACS Publications
A series of 2-thiazolylhydrazone derivatives have been investigated for the ability to inhibit
the activity of the A and B isoforms of monoamine oxidase (MAO) selectively. All of the …
the activity of the A and B isoforms of monoamine oxidase (MAO) selectively. All of the …
(Thiazol-2-yl) hydrazone derivatives from acetylpyridines as dual inhibitors of MAO and AChE: synthesis, biological evaluation and molecular modeling studies
M D'Ascenzio, P Chimenti, MC Gidaro… - Journal of Enzyme …, 2015 - Taylor & Francis
Abstract Several (thiazol-2-yl) hydrazone derivatives from 2-, 3-and 4-acetylpyridine were
synthesized and tested against human monoamine oxidase (hMAO) A and B enzymes. Most …
synthesized and tested against human monoamine oxidase (hMAO) A and B enzymes. Most …
Monoamine oxidase inhibitory activity of novel pyrazoline analogues: Curcumin based design and synthesis
A series of new 2-methoxy-4-(5-phenyl-4, 5-dihydro-1 H-pyrazol-3-yl) phenolderivatives, 4–
13, were synthesized and tested for their human MAO inhibitory activity. All the compounds …
13, were synthesized and tested for their human MAO inhibitory activity. All the compounds …
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