Next-generation derivatization reagents optimized for enhanced product ion formation in photodissociation-mass spectrometry of fatty acids
VR Narreddula, BI McKinnon, SJP Marlton… - Analyst, 2021 - pubs.rsc.org
Ultraviolet-photodissociation (UVPD) mass spectrometry is an emerging analytical tool for
structural elucidation of biomolecules including lipids. Gas phase UVPD of ionised fatty …
structural elucidation of biomolecules including lipids. Gas phase UVPD of ionised fatty …
Rapid differentiation of isomeric lipids by photodissociation mass spectrometry of fatty acid derivatives
HT Pham, AJ Trevitt, TW Mitchell… - … in Mass Spectrometry, 2013 - Wiley Online Library
RATIONALE Both traditional electron ionization and electrospray ionization tandem mass
spectrometry have demonstrated limitations in the unambiguous identification of fatty acids …
spectrometry have demonstrated limitations in the unambiguous identification of fatty acids …
Introduction of a fixed-charge, photolabile derivative for enhanced structural elucidation of fatty acids
Fatty acids are a structurally diverse category of lipids with a myriad of biochemical
functions, which includes their role as building blocks of more complex lipids (eg …
functions, which includes their role as building blocks of more complex lipids (eg …
Structural elucidation of hydroxy fatty acids by photodissociation mass spectrometry with photolabile derivatives
VR Narreddula, P Sadowski… - Rapid …, 2020 - Wiley Online Library
Rationale Eicosanoids are short‐lived bio‐responsive lipids produced locally from oxidation
of polyunsaturated fatty acids (FAs) via a cascade of enzymatic or free radical reactions …
of polyunsaturated fatty acids (FAs) via a cascade of enzymatic or free radical reactions …
[HTML][HTML] Site-specific photochemical reaction for improved C= C location analysis of unsaturated lipids by ultraviolet photodissociation
Unraveling the complexity of the lipidome requires the development of novel approaches to
facilitate structural identification and characterization of lipid species with isomer-level …
facilitate structural identification and characterization of lipid species with isomer-level …
Evaluation of ultraviolet photodissociation tandem mass spectrometry for the structural assignment of unsaturated fatty acid double bond positional isomers
M Fang, Y Rustam, M Palmieri, OM Sieber… - Analytical and …, 2020 - Springer
Fatty acids are a major source of structural diversity within the lipidome due to variations in
their acyl chain lengths, branching, and cyclization, as well as the number, position, and …
their acyl chain lengths, branching, and cyclization, as well as the number, position, and …
IR and UV photodissociation as analytical tools for characterizing lipid A structures
The utility of 193-nm ultraviolet photodissociation (UVPD) and 10.6-μm infrared multiphoton
dissociation (IRMPD) for the characterization of lipid A structures was assessed in an ion …
dissociation (IRMPD) for the characterization of lipid A structures was assessed in an ion …
Double bond characterization of free fatty acids directly from biological tissues by ultraviolet photodissociation
Free fatty acids (FA) are a vital component of cells and are critical to cellular structure and
function, so much so that alterations in FA are often associated with cell malfunction and …
function, so much so that alterations in FA are often associated with cell malfunction and …
Enhancing the signal-to-noise of diagnostic fragment ions of unsaturated glycerophospholipids via precursor exclusion ultraviolet photodissociation mass …
SWJ Shields, JD Sanders, JS Brodbelt - Analytical chemistry, 2022 - ACS Publications
Understanding and elucidating the diverse structures and functions of lipids has motivated
the development of many innovative tandem mass spectrometry (MS/MS) strategies. Higher …
the development of many innovative tandem mass spectrometry (MS/MS) strategies. Higher …
Ultraviolet photodissociation mass spectrometry for analysis of biological molecules
JS Brodbelt, LJ Morrison, I Santos - Chemical reviews, 2019 - ACS Publications
The development of new ion-activation/dissociation methods continues to be one of the most
active areas of mass spectrometry owing to the broad applications of tandem mass …
active areas of mass spectrometry owing to the broad applications of tandem mass …