Background Oxytocin (OXT) modulates several aspects of social behavior. Intranasal OXT is
a leading candidate for treating social deficits in patients with autism spectrum disorder, and …

The evolutionarily highly conserved neuropeptide oxytocin is a key mediator of social and
emotional behavior in mammals, including humans. A common variant (rs53576) in the …

Oxytocin and the oxytocin receptor (OXTR) play an important role in a large variety of social
behaviors. The oxytocinergic system interacts with environmental cues and is highly …

Difficulties in appropriate social and communicative behaviors are the most prevalent and
core symptoms of autism spectrum disorders (ASDs). Although recent intensive research …

The quantitative genetic contribution to antisocial behavior is well established, but few, if
any, genetic variants are established as risk factors. Emerging evidence suggests that the …

Background Common variants in the oxytocin receptor gene (OXTR) have been shown to
influence social and affective behavior and to moderate the effect of adverse experiences on …

Oxytocin plays a vital role in social behavior and homeostatic processes, with animal models
indicating that oxytocin receptor (OXTR) expression patterns in the brain influence behavior …

Across many mammalian species there exist genetic and biological systems that facilitate
the tendency to be social. Oxytocin is a neuropeptide involved in social-approach behaviors …

Genetic approaches have improved our understanding of the neurobiological basis of social
behavior and cognition. For instance, common polymorphisms of genes involved in oxytocin …

A wealth of studies has implicated oxytocin (Oxt) and its receptors (Oxtr) in the mediation of
social behaviors and social memory in rodents. It has been suggested that failures in this …