Tendon tissue engineering: effects of mechanical and biochemical stimulation on stem cell alignment on cell‐laden hydrogel yarns

C Rinoldi, M Costantini… - Advanced …, 2019 - Wiley Online Library
Fiber‐based approaches hold great promise for tendon tissue engineering enabling the
possibility of manufacturing aligned hydrogel filaments that can guide collagen fiber …

Electrospun fibre diameter, not alignment, affects mesenchymal stem cell differentiation into the tendon/ligament lineage

RD Cardwell, LA Dahlgren… - Journal of tissue …, 2014 - Wiley Online Library
Efforts to develop engineered tendons and ligaments have focused on the use of a
biomaterial scaffold and a stem cell source. However, the ideal scaffold microenvironment to …

[HTML][HTML] Tension stimulation of tenocytes in aligned hyaluronic acid/platelet-rich plasma-polycaprolactone core-sheath nanofiber membrane scaffold for tendon tissue …

CH Chen, DL Li, ADC Chuang, BS Dash… - International journal of …, 2021 - mdpi.com
To recreate the in vivo niche for tendon tissue engineering in vitro, the characteristics of
tendon tissue underlines the use of biochemical and biophysical cues during tenocyte …

An epigenetic bioactive composite scaffold with well-aligned nanofibers for functional tendon tissue engineering

C Zhang, X Wang, E Zhang, L Yang, H Yuan, W Tu… - Acta biomaterialia, 2018 - Elsevier
Poor tendon repair is often a clinical challenge due to the lack of ideal biomaterials.
Electrospun aligned fibers, resembling the ultrastructure of tendon, have been previously …

Construction of tendon replacement tissue based on collagen sponge and mesenchymal stem cells by coupled mechano-chemical induction and evaluation of its …

B Zhang, Q Luo, B Deng, Y Morita, Y Ju, G Song - Acta biomaterialia, 2018 - Elsevier
Tissue engineering is an ideal therapeutic strategy for the development of functional tendon
replacement tissue for tendon repair in the clinic. Currently, the synergistic roles of mechano …

The regulation of tendon stem cell differentiation by the alignment of nanofibers

Z Yin, X Chen, JL Chen, WL Shen, TMH Nguyen, L Gao… - Biomaterials, 2010 - Elsevier
Tendon is a specific connective tissue composed of parallel collagen fibers. The effect of this
tissue-specific matrix orientation on stem cell differentiation has not been investigated. This …

Collagen and chondroitin sulfate functionalized bioinspired fibers for tendon tissue engineering application

H Yuan, X Li, MS Lee, Z Zhang, B Li, H Xuan… - International Journal of …, 2021 - Elsevier
Functional tendon tissue engineering depends on harnessing the biochemical and
biophysical cues of the native tendon extracellular matrix. In this study, we fabricated highly …

Fibre‐based scaffolding techniques for tendon tissue engineering

Y Wu, Y Han, YS Wong, JYH Fuh - Journal of tissue …, 2018 - Wiley Online Library
Tendon refers to a band of tough, regularly arranged, and connective tissue connecting
muscle and bone, transferring strength from muscle to bone, and enabling articular stability …

Aligned fibrous scaffolds for enhanced mechanoresponse and tenogenesis of mesenchymal stem cells

TKH Teh, SL Toh, JCH Goh - Tissue engineering part A, 2013 - liebertpub.com
Topographical cell guidance has been utilized as a tissue-engineering technique to produce
aligned cellular orientation in the regeneration of tendon-and ligament-like tissues. Other …

Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation

S Wu, Y Wang, PN Streubel, B Duan - Acta biomaterialia, 2017 - Elsevier
Non-woven nanofibrous scaffolds have been developed for tendon graft application by
using electrospinning strategies. However, electrospun nanofibrous scaffolds face some …