[HTML][HTML] Regenerative therapies for central nervous system diseases: a biomaterials approach

RY Tam, T Fuehrmann, N Mitrousis… - …, 2014 - nature.com
The central nervous system (CNS) has a limited capacity to spontaneously regenerate
following traumatic injury or disease, requiring innovative strategies to promote tissue and …

Biomaterials for promoting brain protection, repair and regeneration

G Orive, E Anitua, JL Pedraz, DF Emerich - Nature Reviews …, 2009 - nature.com
Biomaterials are likely to have an increasingly important role in the treatment of nervous
system disorders. Recently developed biomaterials can enable and augment the targeted …

Matrices, scaffolds & carriers for cell delivery in nerve regeneration

ZZ Wang, SE Sakiyama-Elbert - Experimental neurology, 2019 - Elsevier
Nerve injuries can be life-long debilitating traumas that severely impact patients' quality of
life. While many acellular neural scaffolds have been developed to aid the process of nerve …

Creating permissive microenvironments for stem cell transplantation into the central nervous system

H Kim, MJ Cooke, MS Shoichet - Trends in biotechnology, 2012 - cell.com
Traumatic injury to the central nervous system (CNS) is highly debilitating, with the clinical
need for regenerative therapies apparent. Neural stem/progenitor cells (NSPCs) are …

Biomaterial scaffolds in regenerative therapy of the central nervous system

Y Wang, H Tan, X Hui - BioMed research international, 2018 - Wiley Online Library
The central nervous system (CNS) is the most important section of the nervous system as it
regulates the function of various organs. Injury to the CNS causes impairment of …

Endogenous and exogenous CNS derived stem/progenitor cell approaches for neurotrauma

I Kulbatski, AJ Mothe, H Nomura… - Current drug targets, 2005 - ingentaconnect.com
Neural stem/progenitor cells capable of generating new neurons and glia, reside in specific
areas of the adult mammalian central nervous system (CNS), including the ependymal …

Design of biomaterials to enhance stem cell survival when transplanted into the damaged central nervous system

MJ Cooke, K Vulic, MS Shoichet - Soft Matter, 2010 - pubs.rsc.org
Following injury to the central nervous system (CNS) there is a cascade of events that leads
to cell death, tissue loss and consequently functional deficit. In response to injury, the CNS …

Cell and biomolecule delivery for tissue repair and regeneration in the central nervous system

IE Donaghue, R Tam, MV Sefton… - Journal of Controlled …, 2014 - Elsevier
Tissue engineering frequently involves cells and scaffolds to replace damaged or diseased
tissue. It originated, in part, as a means of effecting the delivery of biomolecules such as …

Biomaterials for brain tissue engineering

JTS Pettikiriarachchi, CL Parish… - Australian journal of …, 2010 - CSIRO Publishing
Neurological disorders such as traumatic brain injuries or stroke result in neuronal loss and
disruption of the brain parenchyma. Current treatment strategies are limited in that they can …

Strategies for regeneration and repair in the injured central nervous system

MS Shoichet, CC Tate, MD Baumann… - … implants: strategies for …, 2008 - books.google.com
8.1 Introduction................................................................................................ 221 8.1. 1 Traumatic
Injury in the Central Nervous System (CNS): Brain and Spinal Cord …