Cognitive effects of neurotoxic lesions of the nucleus basalis magnocellularis in rats: differential roles for corticopetal versus amygdalopetal projections

RJ Beninger, HC Dringenberg, RJ Boegman… - Neurotoxicity …, 2001 - Springer
The cholinergic hypothesis states that cholinergic neurons of the basal forebrain nucleus
basalis magnocellularis (nbm) that project to cortical and amy-gdalar targets play an …

Nucleus basalis magnocellularis and memory: differential effects of two neurotoxins

AL Markowska, GL Wenk, DS Olton - Behavioral and neural biology, 1990 - Elsevier
Although the cholinergic system is involved in memory, noncholinergic systems may also
contribute to memory. Lesions of the nucleus basalis magnocellularis (NBM) produce …

Nucleus basalis lesions: implication of basoamygdaloid cholinergic pathways in memory

PE Mallet, RJ Beninger, SN Flesher, K Jhamandas… - Brain research …, 1995 - Elsevier
Previous studies have shown a lack of association between cortical choline
acetyltransferase (ChAT) activity and severity of memory impairment following excitotoxic …

Behavioural, biochemical and histochemical effects of different neurotoxic amino acids injected into nucleus basalis magnocellularis of rats

SB Dunnet, IQ Whishaw, GH Jones, ST Bunch - Neuroscience, 1987 - Elsevier
Lesions of the nucleus basalis magnocellularis in rats have been used to investigate
functions of the extrinsic cortical cholinergic system which originates from these neurons …

Microanatomical and electrophysiological changes of the rat dentate gyrus caused by lesions of the nucleus basalis magnocellularis

I Panocka, S Sagratella, AS de Carolis, YC Zeng… - Neuroscience …, 1995 - Elsevier
The effect of unilateral or bilateral lesions of the nucleus basalis magnocellularis (NBM) on
the dentate gyrus of the hippocampus were assessed using microanatomical and …

The basal forebrain-cortical cholinergic system: interpreting the functional consequences of excitotoxic lesions

SB Dunnett, BJ Everitt, TW Robbins - Trends in neurosciences, 1991 - cell.com
Ibotenic acid and kainic acid lesions of the basal forebrain induce profound deficits in
performance on a wide variety of tasks involving discrimination learning and memory. These …

The role of cholinergic projections from the nucleus basalis in memory

A Dekker, DJ Connor, LJ Thal - Neuroscience & Biobehavioral Reviews, 1991 - Elsevier
The behavioral effects of lesions of the nucleus basalis magnocellularis (NBM) are
reviewed, focusing on the anatomical extent of the lesion, the involvement of …

Excitotoxic lesions of basal forebrain cholinergic neurons: effects on learning, memory and attention

JL Muir, KJ Page, DJS Sirinathsinghji… - Behavioural brain …, 1993 - Elsevier
A substantial body of literature has suggested that the memory and learning deficits
associated with Alzheimer's disease are attributable to degeneration of the cholinergic …

Comparison of behavioral effects of nucleus basalis magnocellularis lesions and somatosensory cortex ablation in the rat

DF Wozniak, GR Stewart, S Finger, JW Olney - Neuroscience, 1989 - Elsevier
Cholinergic neurons in the nucleus basalis region of the forebrain project to various portions
of the cerebral cortex, including somatosensory cortex. Degeneration of these neurons and …

Learning and memory deficits after lesions of the nucleus basalis magnocellularis: reversal by physostigmine

CL Murray, HC Fibiger - Neuroscience, 1985 - Elsevier
The role of the cholinergic nucleus basalis magnocellularis in spatial learning and memory
was studied in the rat. Animals received bilateral injections of ibotenic acid (5 μg/μl) into the …