Thermogenic brown or beige adipocytes dissipate energy in the form of heat and thereby
counteract obesity and related metabolic complications. The miRNA cluster miR-130b/301b …

miRNAs are important regulators of differentiation, development, and function of brown and
beige fat cells. In this study, we identify the role of the miR-199a/214 cluster in the regulation …

Members of the microRNA (miR)-30 family have been reported to promote adipogenesis
and inhibit osteogenesis, yet their role in the regulation of thermogenesis remains unknown …

White adipose tissue (WAT) browning may have beneficial effects for treating metabolic
syndrome. miRNA are important regulators of the differentiation, development, and function …

Objective In rodents and humans, besides brown adipose tissue (BAT), islands of
thermogenic adipocytes, termed “brite”(brown-in-white) or beige adipocytes, emerge within …

MicroRNA-30a (miR-30a) impacts adipocyte function, and its expression in white adipose
tissue (WAT) correlates with insulin sensitivity in obesity. Bioinformatic analysis …

Prdm16 determines the bidirectional fate switch of skeletal muscle/brown adipose tissue
(BAT) and regulates the thermogenic gene program of subcutaneous white adipose tissue …

Brown adipose tissue (BAT) dissipates chemical energy as heat and can counteract obesity.
Micro RNA s are emerging as key regulators in development and disease. Combining micro …

Mitochondria are critical in heat generation in brown and beige adipocytes. Mitochondrial
number and function are regulated in response to external stimuli, such as cold exposure …

Recent discoveries of functional brown adipocytes in mammals illuminates their therapeutic
potential for combating obesity and its associated diseases. However, on account of the …