Pyrazolo [1, 5-a] pyrimidines are the dominant motif of many drugs; for instance, zaleplon
and indiplon are sedative agents and ocinaplon was identified as an anxiolytic agent. The …

Pyrazolo pyrimidines are fused heterocyclic ring systems which known as bioisosteres of
adenine, that are necessary for every aspect of cell life. Pyrazolo [1, 5-a] pyrimidines …

Pyrazolopyrimidines are fused heterocyclic ring systems which structurally can consider as
bioisosteres of adenine, which is fundamental for every aspect of cell life. Pyrazolo [3, 4-d] …

Abstract Pyrazolo [1, 5-a] pyrimidine scaffold is one of the privileged hetrocycles in drug
discovery. Its application as a buliding block for developing drug-like candidates has …

Numerous N-heterocycles are indisputably evidenced to exhibit myriad biological activities.
In the recent past, attempts made to condense the various heterocycles have resulted in …

Abstract Pyrazolo [4, 3-d] pyrimidine, a fused heterocycle bearing pyrazole and pyrimidine
portions has gained a significant attention in the field of bioorganic and medicinal chemistry …

Pyrazole and pyridine are important heterocycles whose skeletons are incorporated into
many biologically active natural products and synthetic analogues with interesting …

Pyrazolo [1, 5-a] pyrimidine (PP) derivatives are an enormous family of N-heterocyclic
compounds that possess a high impact in medicinal chemistry and have attracted a great …

Among the menacing diseases, cancer needs the most attention as millions of people are
affected by it worldwide. Genetic and environmental factors play a pivotal role in causing …

Pyrazolopyrimidines are the fused heterocyclic ring systems which structurally resemble
purines which prompted biological investigations to assess their potential therapeutic …