Microbiome and metabolome analyses reveal novel interplay between the skin microbiota and plasma metabolites in psoriasis

D Chen, J He, J Li, Q Zou, J Si, Y Guo, J Yu… - Frontiers in …, 2021 - frontiersin.org
Psoriasis is a chronic inflammatory skin disease that affects millions of people worldwide.
There is still no effective approach for the clinical treatment of psoriasis. This is largely due to …

Metabolomics Reveals Molecular Signatures for Psoriasis Biomarkers and Drug Targets Discovery

Q Song, Y Chen, JQ Ma, W Zhou, JY Song… - Clinical, cosmetic and …, 2023 - Taylor & Francis
Purpose Psoriasis is a chronic, multi-system skin disease that can be influenced by
immunological, environmental, and genetic factors. Plasma metabolomic analysis can …

Research progress of metabolomics in psoriasis

L Guo, H Jin - Chinese Medical Journal, 2023 - journals.lww.com
Psoriasis is a chronic inflammatory skin disease with significant physical and psychological
burdens. The interplay between the innate and adaptive immune systems is thought to …

Exploratory multi-omics analysis reveals host-microbe interactions associated with disease severity in psoriatic skin

Y Yang, P Olah, Z Radai, G Maia, A Salava, V Salo… - …, 2024 - thelancet.com
Summary Background Psoriasis (Pso) is a chronic inflammatory skin disease that poses
both physical and psychological challenges. Dysbiosis of the skin microbiome has been …

Deciphering gut microbiota dysbiosis and corresponding genetic and metabolic dysregulation in psoriasis patients using metagenomics sequencing

S Xiao, G Zhang, C Jiang, X Liu, X Wang… - Frontiers in Cellular …, 2021 - frontiersin.org
Background Increasing evidence has shown that alterations in the intestinal microbiota play
an important role in the pathogenesis of psoriasis. The existing relevant studies focus on …

The skin microbiome and its role in psoriasis: a review

V Celoria, F Rosset, V Pala, P Dapavo… - … : Targets and Therapy, 2023 - Taylor & Francis
The skin microbiome is made of various microorganisms, most of which have the function of
protecting individuals from harmful pathogens, and they are involved in innate and adaptive …

Skin and gut microbiome in psoriasis: gaining insight into the pathophysiology of it and finding novel therapeutic strategies

L Chen, J Li, W Zhu, Y Kuang, T Liu, W Zhang… - Frontiers in …, 2020 - frontiersin.org
Psoriasis affects the health of myriad populations around the world. The pathogenesis is
multifactorial, and the exact driving factor remains unclear. This condition arises from the …

Association of the characteristics of the blood metabolome and gut microbiome with the outcome of methotrexate therapy in psoriasis

Q Qiu, J Deng, H Deng, D Yao, Y Yan, S Ye… - Frontiers in …, 2022 - frontiersin.org
Metabolic status and gut microecology are implicated in psoriasis. Methotrexate (MTX) is
usually the first-line treatment for this disease. However, the relationship between MTX and …

Dysbiosis of gut microbiota and its correlation with dysregulation of cytokines in psoriasis patients

X Zhang, L Shi, T Sun, K Guo, S Geng - BMC microbiology, 2021 - Springer
Background Psoriasis is an inflammatory skin disease associated with multiple
comorbidities and substantially diminishes patients' quality of life. The gut microbiome has …

[HTML][HTML] Multiomic analysis of the gut microbiome in psoriasis reveals distinct host‒microbe associations

HW Chang, D Yan, R Singh, A Bui, K Lee, A Truong… - JID Innovations, 2022 - Elsevier
Psoriasis is a chronic, inflammatory skin disease that affects 2‒3% of the global population.
Besides skin manifestations, patients with psoriasis have increased susceptibility to a …