The isotope distribution, which reflects the number and probabilities of occurrence of
different isotopologues of a molecule, can be theoretically calculated. With the current …

Although access to high‐resolution mass spectrometry (MS), especially in the field of
biomolecular MS, is becoming readily available due to recent advances in MS technology …

Biomolecules generally exist as mixtures of diverse isotopologues that differ in the number
and sites of rare-isotope substitutions. The exact proportion of isotopologues of a …

Background An important aspect of proteomic mass spectrometry involves quantifying and
interpreting the isotope distributions arising from mixtures of macromolecules with different …

In secondary ion mass spectrometry measurement systems, the count rate of isotopes may
vary in time as a particle is consumed during the analysis. Since isotopes are measured …

A classic problem in analytical chemistry has been determination of individual components
in a mixture without availability of the pure individual components. Measurement of the …

Multiple collector mass spectrometry has enabled significant advances in our understanding
of geological, biological, nuclear, and physical processes in terrestrial and extra-terrestrial …

Stable isotope-enriched molecules are used as internal standards and as tracers of in vivo
substrate metabolism. The accurate conversion of measured ratios in the mass spectrometer …

Isotope peak patterns in the mass spectra of chemical compounds result from the
occurrence of polyisotopic elements. The various approaches and programs published for …

Isotope variability due to natural processes provides important information for studying a
variety of complex natural phenomena from the origins of a particular sample to the traces of …