Automated liver fat quantification at nonenhanced abdominal CT for population-based steatosis assessment

PM Graffy, V Sandfort, RM Summers, PJ Pickhardt - Radiology, 2019 - pubs.rsna.org
Background Nonalcoholic fatty liver disease and its consequences are a growing public
health concern requiring cross-sectional imaging for noninvasive diagnosis and …

Liver fat is reproducibly measured using computed tomography in the Framingham Heart Study

EK Speliotes, JM Massaro, U Hoffmann… - Journal of …, 2008 - Wiley Online Library
Abstract Background and Aims: Fatty liver is the hepatic manifestation of obesity, but
community‐based assessment of fatty liver among unselected patients is limited. We sought …

Liver steatosis categorization on contrast-enhanced CT using a fully automated deep learning volumetric segmentation tool: evaluation in 1204 healthy adults using …

PJ Pickhardt, GM Blake, PM Graffy… - American Journal of …, 2021 - Am Roentgen Ray Soc
To listen to the podcast associated with this article, please select one of the following:
iTunes, Google Play, or direct download. BACKGROUND. Hepatic attenuation at …

Two-dimensional convolutional neural network using quantitative US for noninvasive assessment of hepatic steatosis in NAFLD

SK Jeon, JM Lee, I Joo, JH Yoon, G Lee - Radiology, 2023 - pubs.rsna.org
Background Quantitative US (QUS) using radiofrequency data analysis has been recently
introduced for noninvasive evaluation of hepatic steatosis. Deep learning algorithms may …

[HTML][HTML] Comparative assessment and external validation of hepatic steatosis formulae in a community-based setting

TY Jung, MS Kim, HP Hong, KA Kang… - Journal of Clinical …, 2020 - mdpi.com
Several hepatic steatosis formulae have been validated in various cohorts using
ultrasonography. However, none of these studies has been validated in a community-based …

Specificity of unenhanced CT for non-invasive diagnosis of hepatic steatosis: implications for the investigation of the natural history of incidental steatosis

PJ Pickhardt, SH Park, L Hahn, SG Lee, KT Bae… - European …, 2012 - Springer
Objectives To determine a highly specific liver attenuation threshold at unenhanced CT for
biopsy-proven moderate to severe hepatic steatosis (≥ 30% at histology). Methods 315 …

Quantification of liver fat content with CT and MRI: state of the art

J Starekova, D Hernando, PJ Pickhardt, SB Reeder - Radiology, 2021 - pubs.rsna.org
Hepatic steatosis is defined as pathologically elevated liver fat content and has many
underlying causes. Nonalcoholic fatty liver disease (NAFLD) is the most common chronic …

Assessment of hepatic steatosis in nonalcoholic fatty liver disease by using quantitative US

A Han, YN Zhang, AS Boehringer, V Montes, MP Andre… - Radiology, 2020 - pubs.rsna.org
Background Advanced confounder-corrected chemical shift–encoded MRI-derived proton
density fat fraction (PDFF) is a leading parameter for fat fraction quantification in …

Liver fat content measurement with quantitative CT validated against MRI proton density fat fraction: a prospective study of 400 healthy volunteers

Z Guo, GM Blake, K Li, W Liang, W Zhang, Y Zhang… - Radiology, 2020 - pubs.rsna.org
Background Although chemical shift–encoded (CSE) MRI proton density fat fraction (PDFF)
is the current noninvasive reference standard for liver fat quantification, the liver is more …

Hepatic steatosis (fatty liver disease) in asymptomatic adults identified by unenhanced low-dose CT

CJ Boyce, PJ Pickhardt, DH Kim… - American Journal of …, 2010 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to investigate the prevalence of hepatic steatosis
in an asymptomatic US adult population using attenuation values at unenhanced CT as the …