Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), which is thought to result from immune-mediated inflammatory disorders, leads to high …

Background and aims Pharmacological treatment and/or maintenance of remission in
inflammatory bowel diseases (IBD) is currently one of the biggest challenge in the field of …

N-Palmitoylethanolamine or palmitoylethanolamide (PEA) is an anti-inflammatory
compound that was recently shown to exert peroxisome proliferator-activated receptor-α …

Fatty acid amide hydrolase (FAAH) is the enzyme crucially involved in the modulation of
physiological processes mediated by anandamide (AEA), as well as other …

Background Recent studies suggest a role for the endocannabinoid system, including fatty
acid amide hydrolase (FAAH), in intestinal inflammation. Aim To analyse FAAH expression …

Background & Aims: Fatty acid amide hydrolase (FAAH) catalyzes the hydrolysis both of the
endocannabinoids (which are known to inhibit intestinal motility) and other bioactive amides …

Background The endogenous cannabinoid system (ECS) plays a crucial role in multiple
physiological processes in the central nervous system and in the periphery. The discovery …

The endocannabinoid (EC) system mediates protection against intestinal inflammation. In
this study, we investigated the effects of blocking EC degradation or cellular reuptake in …

BACKGROUND AND PURPOSE Gastrointestinal (GI) motility is regulated in part by fatty
acid ethanolamides (FAEs), including the endocannabinoid (EC) anandamide (AEA). The …

Crohn's disease and ulcerative colitis are two major forms of inflammatory bowel diseases
(IBD), which are chronic inflammatory disorders of the gastrointestinal tract. These …