Polydopamine as the antigen delivery nanocarrier for enhanced immune response in tumor immunotherapy

N Wang, Y Yang, X Wang, X Tian, W Qin… - ACS Biomaterials …, 2019 - ACS Publications
This study aimed to investigate the efficacy of polydopamine nanoparticles (Pdop-NPs) as a
subcutaneous antigen delivery vehicle in antitumor therapy. The nanoparticles were …

Polydopamine nanoparticles carrying tumor cell lysate as a potential vaccine for colorectal cancer immunotherapy

X Wang, N Wang, Y Yang, X Wang, J Liang… - Biomaterials …, 2019 - pubs.rsc.org
Polydopamine nanoparticles (PDA NPs) were prepared via dopamine self-polymerization;
then, tumor cell lysate (TCL) was covalently attached onto the PDA NPs. The TCL loading …

Mussel-Inspired Polydopamine: A Biocompatible and Ultrastable Coating for Nanoparticles in Vivo

X Liu, J Cao, H Li, J Li, Q Jin, K Ren, J Ji - ACS nano, 2013 - ACS Publications
Bioinspired polydopamine (PDA) has served as a universal coating to nanoparticles (NPs)
for various biomedical applications. However, one remaining critical question is whether the …

Development of multifunctional polydopamine nanoparticles as a theranostic nanoplatform against cancer cells

J Wang, Y Guo, J Hu, W Li, Y Kang, Y Cao, H Liu - Langmuir, 2018 - ACS Publications
Although demanding, the development of multifunctional theranostic nanoplatforms is
attracting considerable worldwide interest. Herein, a theranostic nanoplatform with …

The pH-controlled nanoparticles size of polydopamine for anti-cancer drug delivery

CC Ho, SJ Ding - Journal of Materials Science: Materials in Medicine, 2013 - Springer
A facile method was used to prepare polydopamine (PDA) nanoparticles. The effect of the
initial pH of the dopamine solution on the formation kinetics, chemical structure, and …

Surface modification of doxorubicin-loaded nanoparticles based on polydopamine with pH-sensitive property for tumor targeting therapy

D Bi, L Zhao, R Yu, H Li, Y Guo, X Wang, M Han - Drug delivery, 2018 - Taylor & Francis
One major challenge of current surface modification of nanoparticles is the demand for
chemical reactive polymeric layers, such modification is always complicated, inefficient, and …

Application of polydopamine in tumor targeted drug delivery system and its drug release behavior

Z Wang, Y Duan, Y Duan - Journal of Controlled Release, 2018 - Elsevier
Inspired by the bionics of marine mussels, polydopamine (PDA), a new polymer with unique
physicochemical properties was discovered. Due to its simple preparation, good …

Doxorubicin and PD-L1 siRNA co-delivery with stem cell membrane-coated polydopamine nanoparticles for the targeted chemoimmunotherapy of PCa bone …

X Mu, M Zhang, A Wei, F Yin, Y Wang, K Hu, J Jiang - Nanoscale, 2021 - pubs.rsc.org
Programmed cell death ligand 1 (PD-L1) blockade has achieved great success in cancer
immunotherapy. PD-L1 siRNA can restore the immune anti-tumor activity of T cells by …

A novel high drug loading mussel-inspired polydopamine hybrid nanoparticle as a pH-sensitive vehicle for drug delivery

J Hou, C Guo, Y Shi, E Liu, W Dong, B Yu, S Liu… - International Journal of …, 2017 - Elsevier
A novel high drug loading pH-cleavable polymer hybrid nanoparticle was prepared via
doxorubicin (DOX) grafted onto PEGylated, mussel-inspired polydopamine (PDA) and then …

Hydroxyethyl starch stabilized polydopamine nanoparticles for cancer chemotherapy

H Wu, H Hu, J Wan, Y Li, Y Wu, Y Tang, C Xiao… - Chemical Engineering …, 2018 - Elsevier
Bio-inspired polydopamine (PDA) based nanomaterials, particularly nanoparticles (NPs),
received tremendous attention and have been applied to various fields, including drug …