Construction and validation of a folate metabolism-related gene signature for predicting prognosis in HNSCC

L Wang, Y He, Y Bai, S Zhang, B Pang, A Chen… - Journal of Cancer …, 2024 - Springer
Purpose Metabolic reprogramming is currently considered a hallmark of tumor and immune
development. It is obviously of interest to identify metabolic enzymes that are associated with …

[HTML][HTML] Metabolism-associated molecular classification and prognosis signature of head and neck squamous cell carcinoma

M Jiang, X Gu, Y Xu, J Wang - Heliyon, 2024 - cell.com
Although the fundamental processes and chemical changes in metabolic programs have
been elucidated in many cancers, the expression patterns of metabolism-related genes in …

A novel prognostic signature based on metabolism-related genes to predict survival and guide personalized treatment for head and neck squamous carcinoma

Y Li, Y Weng, Y Pan, Z Huang, X Chen, W Hong… - Frontiers in …, 2021 - frontiersin.org
Metabolic reprogramming contributes to patient prognosis. Here, we aimed to reveal the
comprehensive landscape in metabolism of head and neck squamous carcinoma (HNSCC) …

A novel metabolic-related gene signature for predicting clinical prognosis and immune microenvironment in head and neck squamous cell carcinoma

Y Cao, Z Dai, G Xie, G Liu, L Guo, J Zhang - Experimental Cell Research, 2023 - Elsevier
Objectives Metabolic reprogramming is not only an essential hallmark in the progression of
head and neck squamous cell carcinoma (HNSCC), but also an important regulator of …

In Silico analysis and linking of metabolism-related genes with the immune landscape in head and neck squamous cell carcinoma

J Zhang, R Cao, J Peng, Q Hu, J Xia, B Cheng - Biocell, 2022 - search.proquest.com
Metabolic reprogramming and immunologic suppression are two critical characteristics
promoting the progression of head and neck squamous cell carcinoma (HNSCC). The …

Cellular hierarchy framework based on single-cell/multi-patient sample sequencing reveals metabolic biomarker PYGL as a therapeutic target for HNSCC

J Guan, X Xu, G Qiu, C He, X Lu, K Wang, X Liu… - Journal of Experimental …, 2023 - Springer
Background A growing body of research has revealed the connection of metabolism
reprogramming and tumor progression, yet how metabolism reprogramming affects inter …

Identification of a metabolic reprogramming‐related signature associated with prognosis and immune microenvironment of head and neck squamous cell carcinoma …

W Qiang, Y Dai, X Xing, X Sun - Cancer Medicine, 2022 - Wiley Online Library
Background Metabolic reprogramming is one of the essential features of tumorigenesis.
Herein, this study aimed to develop a novel metabolism‐related gene signature for head …

A Prognostic Model of Head and Neck Cancer Based on Amino Acid Metabolism-Related Signature and Its Implication for Immunosuppressive Microenvironment

X Li, D Li, J Li, Y Chen, Z Cai, F Tan - International Journal of Molecular …, 2023 - mdpi.com
Amino acid metabolism has been implicated in tumorigenesis and tumor progression.
Alterations in intracellular and extracellular metabolites associated with metabolic …

Integration of transcriptomics and metabolomics reveals a novel gene signature guided by FN1 associated with immune response in oral squamous cell carcinoma …

Y Peng, D Yin, X Li, K Wang, W Li, Y Huang… - Journal of Cancer …, 2023 - Springer
Purpose Oral squamous cell carcinomas (OSCCs) are primary head and neck malignant
tumours with a high incidence and mortality. However, the molecular mechanisms involved …

A robust metabolic enzyme-based prognostic signature for head and neck squamous cell carcinoma

Z Mai, H Chen, M Huang, X Zhao, L Cui - Frontiers in Oncology, 2022 - frontiersin.org
Background Head and neck squamous cell carcinoma (HNSCC) is still a menace to public
wellbeing globally. However, the underlying molecular events influencing the …