Mesenchymal stem cells and thermal annular procedures for discogenic pain: a systematic review with pooled analysis
J DesRochers, R DesRochers, D Patel… - Pain …, 2024 - Taylor & Francis
Aim: Compare the effectiveness of mesenchymal stem cell injection therapies (MSC) and
thermal annular procedures for the treatment of discogenic lower back pain. Materials & …
thermal annular procedures for the treatment of discogenic lower back pain. Materials & …
The effectiveness of intradiscal biologic treatments for discogenic low back pain: a systematic review
BJ Schneider, C Hunt, A Conger, W Qu, TP Maus… - The Spine Journal, 2022 - Elsevier
ABSTRACT BACKGROUND CONTEXT There are limited treatments for discogenic low back
pain. Intradiscal injections of biologic agents such as platelet-rich plasma (PRP) or stem …
pain. Intradiscal injections of biologic agents such as platelet-rich plasma (PRP) or stem …
Current understanding of safety and efficacy of stem cell therapy for discogenic pain—A systematic review of human studies
CL Hunt, S Shen, A Nassr, AJ van Wijnen… - Techniques in Regional …, 2015 - Elsevier
This study is a systematic review of human clinical studies of stem cell therapy for discogenic
pain. To summarize the current human trials and feasibility studies involving mesenchymal …
pain. To summarize the current human trials and feasibility studies involving mesenchymal …
Low-dose mesenchymal stem cell therapy for discogenic pain: safety and efficacy results from a 1-year feasibility study
Aim: To evaluate safety and efficacy of low dose autologous adipose-derived mesenchymal
stem cells (ADMSCs) for treatment of disc degeneration resulting in low back pain (LBP) …
stem cells (ADMSCs) for treatment of disc degeneration resulting in low back pain (LBP) …
The analgesic efficacy of intradiscal injection of bone marrow aspirate concentrate and culture-expanded bone marrow mesenchymal stromal cells in discogenic pain …
YF Her, E Kubrova, GA Martinez Alvarez… - Journal of Pain …, 2022 - Taylor & Francis
Pain originating from the intervertebral disc (discogenic pain) is a prevalent manifestation of
low back pain and is often challenging to treat. Of recent interest, regenerative medicine …
low back pain and is often challenging to treat. Of recent interest, regenerative medicine …
Stem cells and discogenic back pain
L Miranda, M Quaranta, F Oliva… - British Medical …, 2023 - academic.oup.com
Background Chronic low back pain, common from the sixth decade, negatively impacts the
quality of life of patients and health care systems. Recently, mesenchymal stem cells (MSCs) …
quality of life of patients and health care systems. Recently, mesenchymal stem cells (MSCs) …
Treatment of lumbar degenerative disc disease-associated radicular pain with culture-expanded autologous mesenchymal stem cells: a pilot study on safety and …
C Centeno, J Markle, E Dodson, I Stemper… - Journal of Translational …, 2017 - Springer
Background Degenerative disc disease (DDD) is a common cause of lower back pain with
radicular symptoms and has a significant socioeconomic impact given the associated …
radicular symptoms and has a significant socioeconomic impact given the associated …
[HTML][HTML] Stem cell therapy in discogenic back pain
AH Barakat, VA Elwell, KS Lam - Journal of Spine Surgery, 2019 - ncbi.nlm.nih.gov
Chronic low back pain has both substantial social and economic impacts on patients and
healthcare budgets. Adding to the magnitude of the problem is the difficulty in identifying the …
healthcare budgets. Adding to the magnitude of the problem is the difficulty in identifying the …
Perspective on Intradiscal Therapies for Lumbar Discogenic Pain: State of the Science, Knowledge Gaps, and Imperatives for Clinical Adoption
MP Lorio, JL Tate, TJ Myers, JE Block… - Journal of Pain …, 2024 - Taylor & Francis
Specific clinical diagnostic criteria have established a consensus for defining patients with
lumbar discogenic pain. However, if conservative medical management fails, these patients …
lumbar discogenic pain. However, if conservative medical management fails, these patients …
Cell-based therapies for lumbar discogenic low back pain: systematic review and single-arm meta-analysis
T Wu, H Song, Y Dong, J Li - Spine, 2018 - journals.lww.com
Study Design. A systematic review and single-arm meta-analysis of clinical trials. Objective.
To assess the efficacy of mesenchymal stem cells or chondrocyte in patients with discogenic …
To assess the efficacy of mesenchymal stem cells or chondrocyte in patients with discogenic …
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