Aim: Compare the effectiveness of mesenchymal stem cell injection therapies (MSC) and
thermal annular procedures for the treatment of discogenic lower back pain. Materials & …

ABSTRACT BACKGROUND CONTEXT There are limited treatments for discogenic low back
pain. Intradiscal injections of biologic agents such as platelet-rich plasma (PRP) or stem …

This study is a systematic review of human clinical studies of stem cell therapy for discogenic
pain. To summarize the current human trials and feasibility studies involving mesenchymal …

Aim: To evaluate safety and efficacy of low dose autologous adipose-derived mesenchymal
stem cells (ADMSCs) for treatment of disc degeneration resulting in low back pain (LBP) …

Pain originating from the intervertebral disc (discogenic pain) is a prevalent manifestation of
low back pain and is often challenging to treat. Of recent interest, regenerative medicine …

Background Chronic low back pain, common from the sixth decade, negatively impacts the
quality of life of patients and health care systems. Recently, mesenchymal stem cells (MSCs) …

Background Degenerative disc disease (DDD) is a common cause of lower back pain with
radicular symptoms and has a significant socioeconomic impact given the associated …

Chronic low back pain has both substantial social and economic impacts on patients and
healthcare budgets. Adding to the magnitude of the problem is the difficulty in identifying the …

Specific clinical diagnostic criteria have established a consensus for defining patients with
lumbar discogenic pain. However, if conservative medical management fails, these patients …

Study Design. A systematic review and single-arm meta-analysis of clinical trials. Objective.
To assess the efficacy of mesenchymal stem cells or chondrocyte in patients with discogenic …