Mammalian septins are GTP-binding proteins the functions of which are not well understood.
Knockdown of SEPT2, 6, and 7 causes stress fibers to disintegrate and cells to lose polarity …

Septins are cytoskeletal proteins that assemble into nonpolar filaments. They are critical in
diverse cellular functions, acting as scaffolds for protein recruitment and as diffusion barriers …

Background Septin2 is a member of a highly conserved GTPase family found in fungi and
animals. Septins have been implicated in a diversity of cellular processes including …

Septins are a highly conserved family of proteins in eukaryotes that is recognized as a novel
component of the cytoskeleton. Septin 9 (SEPT9) interacts directly with actin filaments and …

Septins are a highly conserved family of GTP-binding cytoskeletal proteins implicated in
multiple cellular functions, including membrane transport, apoptosis, cell polarity, cell cycle …

SEPT9_v1, the largest transcript of the septin gene family member, SEPT9, encodes a septin
isoform implicated in the tumorigenic transformation of mammary epithelial cells. High levels …

Septins are a novel class of GTP-binding cytoskeletal proteins evolutionarily conserved from
yeast to mammals and have now been found to play a contributing role in a broad range of …

Abstract Septin9 (Sept9) is a member of the filament-forming septin family of structural
proteins and is associated with a variety of cancers and with hereditary neuralgic …

Septins are conserved guanine nucleotide-binding proteins that polymerize into filaments at
the cell cortex or in association with other cytoskeletal proteins, such as actin or …

Septins are filamentous guanosine triphosphatase–binding proteins that are required for
cytokinesis in a wide range of organisms from yeast to man. Several septins, including …