Nitric oxide–releasing drugs

C Napoli, LJ Ignarro - Annual review of pharmacology and …, 2003 - annualreviews.org
Pharmacological compounds that release nitric oxide (NO) have been useful tools for
evaluating the broad role of NO in physiology and therapeutics. NO deficiency has been …

Nitric oxide (NO)-related pharmaceuticals: contemporary approaches to therapeutic NO modulation

DR Janero - Free Radical Biology and Medicine, 2000 - Elsevier
The biologically important gaseous radical, nitric oxide (NO), is a versatile chemical entity
that enters into regulatory, protective, and adverse interactions with biomolecules and cells …

Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview

LJ Ignarro, C Napoli, J Loscalzo - Circulation research, 2002 - Am Heart Assoc
Nitric oxide (NO) mediates multiple physiological and pathophysiological processes in the
cardiovascular system. Pharmacological compounds that release NO have been useful tools …

Nitric oxide donor drugs: an update on pathophysiology and therapeutic potential

R Scatena, P Bottoni, GE Martorana… - Expert opinion on …, 2005 - Taylor & Francis
The discovery of the multiple physiological and pathophysiological processes in which nitric
oxide (NO) is involved has promoted a great number of pharmacological researches to …

Nitric oxide donor drugs

IL Megson - Drugs Future, 2000 - access.portico.org
Research over the past 20 years has identified endogenous nitric oxide (NO) as a key
messenger molecule in the cardiovascular, nervous and immune systems. Research to date …

[PDF][PDF] Nitric oxide as a unique signaling molecule in the

L Ignarro - Journal of physiology and pharmacology, 2002 - jpp.krakow.pl
In retrospect, basic research in the fields of NO and cyclic GMP during thev past two
decades appears to have followed a logical course beginning with the findings that NO and …

Pharmacological modulation of nitric oxide release: new pharmacological perspectives, potential benefits and risks

R Scatena, P Bottoni, A Pontoglio… - Current medicinal …, 2010 - ingentaconnect.com
Nitric oxide is becoming an increasingly important signalling molecule implicated in a
growing number of physiological and pathophysiological processes. Moreover, with the …

Nitric oxide-based possibilities for pharmacotherapy

I Pörsti, I Paakkari - Annals of medicine, 1995 - Taylor & Francis
The goal of nitric oxide (NO) based pharmacotherapy is to reach proper homeostasis of NO
metabolism in the target tissue where endogenous production of NO is either too weak or …

Nitric oxide: an ubiquitous messenger

A Berdeaux - Fundamental & clinical pharmacology, 1993 - Wiley Online Library
During the last decade, a multitude of experimental arguments have led to the concept that
EDRF is nitric oxide (NO), a messenger not only involved in the control of vasomotor tone …

Recent developments in nitric oxide donor drugs

MR Miller, IL Megson - British journal of pharmacology, 2007 - Wiley Online Library
During the 1980s, the free radical, nitric oxide (NO), was discovered to be a crucial
signalling molecule, with wide‐ranging functions in the cardiovascular, nervous and immune …