The TiHoCL panel for canine lymphoma: a feasibility study integrating functional genomics and network biology approaches for comparative oncology targeted NGS …

S Fibi-Smetana, C Inglis, D Schuster… - Frontiers in veterinary …, 2023 - frontiersin.org
Targeted next-generation sequencing (NGS) enables the identification of genomic variants
in cancer patients with high sensitivity at relatively low costs, and has thus opened the era to …

[HTML][HTML] Comparative oncology DNA sequencing of canine T cell lymphoma via human hotspot panel

JT McDonald, A Kritharis, A Beheshti, M Pilichowska… - Oncotarget, 2018 - ncbi.nlm.nih.gov
T-cell lymphoma (TCL) is an uncommon and aggressive form of human cancer. Lymphoma
is the most common hematopoietic tumor in canines (companion animals), with TCL …

[PDF][PDF] Multi-national, multi-center collaboration to develop a novel gene expression tool for comparative translational immuno-oncology

N Mason, C Bailey, E Piazza, AFH Haake, AD Gruber… - Can Res, 2021 - nanostring.com
Abstract NanoString's nCounter Analysis System performs a highly multiplexed, digital
quantification of up to 800 genes in a single reaction. This is achieved via reporter three …

Whole genome sequencing analysis of high confidence variants of B-cell lymphoma in Canis familiaris

A Sparks, JP Woods, D Bienzle, GA Wood… - PLoS …, 2020 - journals.plos.org
Lymphoma (lymphosarcoma) is the second most frequent cancer in dogs and is clinically
comparable to human non-Hodgkin lymphoma. Factors affecting canine lymphoma …

Canine Oncopanel: A capture‐based, NGS platform for evaluating the mutational landscape and detecting putative driver mutations in canine cancers

G Wang, M Wu, AC Durham… - Veterinary and …, 2022 - Wiley Online Library
Canine cancer, a significant cause of mortality in domestic dogs, is a powerful comparative
model for human cancers. Revealing genetic alterations driving the oncogenesis of canine …

Comparative High-Resolution Transcriptome Sequencing of Lymphoma Cell Lines and de novo Lymphomas Reveals Cell-Line-Specific Pathway Dysregulation

L Taher, J Beck, W Liu, C Roolf, JT Soller, BC Rütgen… - Scientific reports, 2018 - nature.com
In dogs as well as humans, lymphoma is one of the most common hematopoietic
malignancies. Furthermore, due to its characteristics, canine lymphoma is recognized as a …

Genomic analysis across 53 canine cancer types reveals novel mutations and high clinical actionability potential

S Sakthikumar, M Warrier, D Whitley… - Veterinary and …, 2024 - Wiley Online Library
A genomic understanding of the oncogenic processes and individual variability of human
cancer has steadily fueled improvement in patient outcomes over the past 20 years …

RNA-Seq analysis of gene expression in 25 cases of canine lymphoma undergoing CHOP chemotherapy

MW Mee, S Faulkner, GA Wood, JP Woods… - BMC Research …, 2022 - Springer
Objectives Canine lymphoma, the most common hematological cancer in dogs, shares
many molecular and clinical characteristics with human Non-Hodgkin lymphoma (NHL). The …

Evaluation of 41 single nucleotide polymorphisms in canine diffuse large B-cell lymphomas using MassARRAY

S Sirivisoot, T Kasantikul, S Techangamsuwan… - Scientific reports, 2022 - nature.com
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of lymphoma in dogs
with a multicentric form. This study aimed to assemble 41 variants of the previously reported …

Mutational landscape of canine B-cell lymphoma profiled at single nucleotide resolution by RNA-seq

D Giannuzzi, L Marconato, L Cascione, S Comazzi… - PLoS …, 2019 - journals.plos.org
The genomic landscape in human B-cell lymphoma has revealed several somatic mutations
and potentially relevant germline alterations affecting therapy and prognosis. Also …