The TiHoCL panel for canine lymphoma: a feasibility study integrating functional genomics and network biology approaches for comparative oncology targeted NGS …
S Fibi-Smetana, C Inglis, D Schuster… - Frontiers in veterinary …, 2023 - frontiersin.org
Targeted next-generation sequencing (NGS) enables the identification of genomic variants
in cancer patients with high sensitivity at relatively low costs, and has thus opened the era to …
in cancer patients with high sensitivity at relatively low costs, and has thus opened the era to …
[HTML][HTML] Comparative oncology DNA sequencing of canine T cell lymphoma via human hotspot panel
T-cell lymphoma (TCL) is an uncommon and aggressive form of human cancer. Lymphoma
is the most common hematopoietic tumor in canines (companion animals), with TCL …
is the most common hematopoietic tumor in canines (companion animals), with TCL …
[PDF][PDF] Multi-national, multi-center collaboration to develop a novel gene expression tool for comparative translational immuno-oncology
Abstract NanoString's nCounter Analysis System performs a highly multiplexed, digital
quantification of up to 800 genes in a single reaction. This is achieved via reporter three …
quantification of up to 800 genes in a single reaction. This is achieved via reporter three …
Whole genome sequencing analysis of high confidence variants of B-cell lymphoma in Canis familiaris
Lymphoma (lymphosarcoma) is the second most frequent cancer in dogs and is clinically
comparable to human non-Hodgkin lymphoma. Factors affecting canine lymphoma …
comparable to human non-Hodgkin lymphoma. Factors affecting canine lymphoma …
Canine Oncopanel: A capture‐based, NGS platform for evaluating the mutational landscape and detecting putative driver mutations in canine cancers
G Wang, M Wu, AC Durham… - Veterinary and …, 2022 - Wiley Online Library
Canine cancer, a significant cause of mortality in domestic dogs, is a powerful comparative
model for human cancers. Revealing genetic alterations driving the oncogenesis of canine …
model for human cancers. Revealing genetic alterations driving the oncogenesis of canine …
Comparative High-Resolution Transcriptome Sequencing of Lymphoma Cell Lines and de novo Lymphomas Reveals Cell-Line-Specific Pathway Dysregulation
In dogs as well as humans, lymphoma is one of the most common hematopoietic
malignancies. Furthermore, due to its characteristics, canine lymphoma is recognized as a …
malignancies. Furthermore, due to its characteristics, canine lymphoma is recognized as a …
Genomic analysis across 53 canine cancer types reveals novel mutations and high clinical actionability potential
S Sakthikumar, M Warrier, D Whitley… - Veterinary and …, 2024 - Wiley Online Library
A genomic understanding of the oncogenic processes and individual variability of human
cancer has steadily fueled improvement in patient outcomes over the past 20 years …
cancer has steadily fueled improvement in patient outcomes over the past 20 years …
RNA-Seq analysis of gene expression in 25 cases of canine lymphoma undergoing CHOP chemotherapy
Objectives Canine lymphoma, the most common hematological cancer in dogs, shares
many molecular and clinical characteristics with human Non-Hodgkin lymphoma (NHL). The …
many molecular and clinical characteristics with human Non-Hodgkin lymphoma (NHL). The …
Evaluation of 41 single nucleotide polymorphisms in canine diffuse large B-cell lymphomas using MassARRAY
S Sirivisoot, T Kasantikul, S Techangamsuwan… - Scientific reports, 2022 - nature.com
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of lymphoma in dogs
with a multicentric form. This study aimed to assemble 41 variants of the previously reported …
with a multicentric form. This study aimed to assemble 41 variants of the previously reported …
Mutational landscape of canine B-cell lymphoma profiled at single nucleotide resolution by RNA-seq
D Giannuzzi, L Marconato, L Cascione, S Comazzi… - PLoS …, 2019 - journals.plos.org
The genomic landscape in human B-cell lymphoma has revealed several somatic mutations
and potentially relevant germline alterations affecting therapy and prognosis. Also …
and potentially relevant germline alterations affecting therapy and prognosis. Also …