Salt taste, the taste of sodium chloride (NaCl), is mechanistically one of the most complex
and puzzling among basic tastes. Sodium has essential functions in the body but causes …

Maintenance of sodium levels is crucial to maintain normal physiology. Accordingly, the
unique taste quality of saltiness allows animals, including humans, to identify sources of …

How taste buds detect NaCl remains poorly understood. Among other problems, applying
taste-relevant concentrations of NaCl (50–500 mm) onto isolated taste buds or cells exposes …

Salt taste in mammals can trigger two divergent behavioural responses. In general,
concentrated saline solutions elicit robust behavioural aversion, whereas low concentrations …

Salt taste sensation is multifaceted: NaCl at low or high concentrations is preferably or
aversively perceived through distinct pathways. Cl− is thought to participate in taste …

A principalprocess in the homeostatic control of sodium levels is salt intake, and the sense of
taste has a primary role in regulating ingestion. Because ingestion of sodium chloride (NaCI) …

Responses in the amiloride-insensitive (AI) pathway, one of the two pathways mediating
salty taste in mammals, are modulated by the size of the anion of a salt. This “anion effect” …

The tastes of salts to humans are complex. NaCl is the most purely salty of all salts, but even
this stimulus tastes sweet at low concentrations and somewhat sour at mid-range intensities …

Each taste modality is generally encoded by a single, molecularly defined, population of
sensory cells. However, salt stimulates multiple taste pathways in mammals and insects …

Solutions of table salt (NaCl) elicit several tastes, including of course saltiness but also
sweet, sour, and bitter. This brief review touches on some of the mileposts concerning what …