Effects of the domestic thyroid stimulating hormone receptor (TSHR) variant on the hypothalamic-pituitary-thyroid axis and behavior in chicken

A Fallahshahroudi, M Johnsson, E Sorato… - Genetics, 2021 - academic.oup.com
Domestic chickens are less fearful, have a faster sexual development, grow bigger, and lay
more eggs than their primary ancestor, the red junglefowl. Several candidate genetic …

The effect of a mutation in the thyroid stimulating hormone receptor (TSHR) on development, behaviour and TH levels in domesticated chickens

AC Karlsson, F Svemer, J Eriksson, VM Darras… - PLoS …, 2015 - journals.plos.org
The thyroid stimulating hormone receptor (TSHR) has been suggested to be a
“domestication locus” in the chicken, due to a strong selective sweep over the gene found in …

A domestication related mutation in the thyroid stimulating hormone receptor gene (TSHR) modulates photoperiodic response and reproduction in chickens

AC Karlsson, A Fallahshahroudi, H Johnsen… - General and …, 2016 - Elsevier
The thyroid stimulating hormone receptor gene (TSHR) has been suggested to be a
“domestication locus” in the chicken. A strong selective sweep over TSHR in domestic …

Structural and dynamic analysis of G558R mutation in chicken TSHR gene shows altered signal transduction and corroborates its role as a domestication gene

A Grottesi, F Gabbianelli, A Valentini… - Animal …, 2020 - Wiley Online Library
The thyroid‐stimulating hormone receptor (TSHR) has been indicated as a putative
domestication gene in chicken. Comparison of WGS identified a variant in residue 558 of the …

Identification of unique thyrotropin receptor (TSHR) splice variants in the chicken: The chicken TSHR gene revisited

SVH Grommen, S Taniuchi, VM Darras… - General and …, 2008 - Elsevier
We previously described the cloning of the full-length chicken thyrotropin receptor (TSHRa)
and two splice variants, lacking exon 3 (TSHRb) or both exons 2 and 3 (TSHRc). Here we …

Screen of small fragment mutations within the sheep thyroid stimulating hormone receptor gene associated with litter size

M Li, Q Zhou, Y Pan, X Lan, Q Zhang, C Pan… - Animal …, 2023 - Taylor & Francis
The thyroid stimulating hormone receptor (TSHR), a glycoprotein hormone receptor, plays
an important role in metabolic regulation and photoperiod control in the time of reproduction …

Molecular cloning and variant analysis of the TSHR gene in goose (Anser cygnoides)

C Wang, Y Liu, G Li, S Gong, Y Yang… - British poultry …, 2020 - Taylor & Francis
The thyroid-stimulating hormone receptor (TSHR) is a glycoprotein hormone receptor which
has a pivotal role in metabolic regulation and photoperiod control during reproduction in …

Molecular cloning, tissue distribution, and ontogenic thyroidal expression of the chicken thyrotropin receptor

SVH Grommen, S Taniuchi, T Janssen… - …, 2006 - academic.oup.com
TSH and the interaction with its receptor (TSHR) in the thyroid gland play a crucial role in the
pituitary-thyroid axis of all vertebrates. Released upon stimulation by TSH, thyroid hormones …

Involvement of thyrotropin-releasing hormone receptor, somatostatin receptor subtype 2 and corticotropin-releasing hormone receptor type 1 in the control of chicken …

B De Groef, KL Geris, J Manzano, J Bernal… - Molecular and Cellular …, 2003 - Elsevier
Thyrotropin or thyroid-stimulating hormone (TSH) secretion in the chicken is controlled by
several hypothalamic hormones. It is stimulated by thyrotropin-releasing hormone (TRH) …

Increasing plasma thyroxine levels during late embryogenesis and hatching in the chicken are not caused by an increased sensitivity of the thyrotropes to …

B De Groef, SVH Grommen… - Journal of …, 2006 - joe.bioscientifica.com
The hatching process in the chicken is accompanied by dramatic changes in plasma thyroid
hormones. The cause of these changes, though crucial for hatching and the onset of …