Peptic ulcers are believed to develop because of increased acid and pepsin secretion, a
reduced mucosal defense mechanism, or a combination of these two abnormalities …

Heterogeneity is the most important consideration in the pathophysiology of peptic ulcer
disease. Acute ulcers and erosions present clinically with gastrointestinal bleeding or …

ALTHOUGH several features of peptic ulcer disease have been elucidated over the past few
years, new questions have replaced those that have been answered. Some of the factors …

It is becoming increasingly apparent that peptic ulcer is not one disease, but a genetically,
etiologically, and pathogenetically heterogeneous group of diseases that share a common …

Recent advanccs have led to improved understanding of peptic ulcer pathophysiology. A
basic paradigm for ulcer disease is the imbalance between the digestive activity of acid and …

This chapter contains sections titled: Introduction Etiology and pathophysiology of peptic
ulcer Other forms of peptic ulcer (non‐Hp, non‐NSAID) Risk factors for peptic ulcer The …

SUMMARY In the United States about four million people have active peptic ulcers and
about 350000 new cases are diagnosed each year. Four times as many duodenal ulcers as …

Newer Concepts in the Pathogenesis of Peptic Ulcer Disease Page 1 Symposium on Peptic
Ulcer Disease Newer Concepts in the Pathogenesis of Peptic Ulcer Disease Andrew Ippoliti …

The familial aggregation of peptic ulcer disease has been well established, as has its
association with such clear-cut genetic factors as blood group O and nonsecretor status …

Peptic ulcer disease usually has periodic exacerbations and remissions. Pain can disappear
without total healing of the ulcer crater and can be absent when an ulcer is present …