Tuberous sclerosis complex is a rare genetic disease associated with mutations in the TSC1
or TSC2 genes, which cause overactivation of the mTOR complex. In the past 5 years …

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that affects multiple
organ systems due to an inactivating variant in either TSC1 or TSC2, resulting in the …

Tuberous Sclerosis Complex (TSC) is a multisystem genetic disorder with variable
phenotypic expression, due to a mutation in one of the two genes, TSC1 and TSC2, and a …

Tuberous sclerosis (also known as tuberous sclerosis complex [TSC]) is a multisystem
genetic disorder that affects almost every organ in the body. Mutations in the TSC1 or TSC2 …

Tuberous sclerosis complex (TSC) is a multisystem disorder that results from heterozygous
mutations in either TSC1 or TSC2. The primary organ systems that are affected include the …

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by the
development of widespread hamartomatous lesions in various organs, including brain, skin …

Over the past decade, there have been numerous advances in our understanding of the
molecular pathogenesis of tuberous sclerosis complex (TSC). Following the identification of …

The autosomal dominant disorder tuberous sclerosis complex (TSC) is characterized by an
array of manifestations both within and outside of the central nervous system (CNS) …

Tuberous sclerosis complex (TSC) is a dominantly inherited disease with high penetrance
and morbidity, and is caused by mutations in either of two genes, TSC1 or TSC2. Most …

Tuberous sclerosis complex (TSC) is an autosomal-dominant or sporadic multisystem
disorder that results from mutations in either TSC1 or TSC2. The primary organs affected …