Accumulating evidence suggests that many classes of DNA repeats exhibit attributes that
distinguish them from other genetic variants, including the fact that they are more liable to …

Tandem repeats are common features of both prokaryote and eukaryote genomes, where
they can be found not only in intergenic regions but also in both the noncoding and coding …

Over a third of the human genome is comprised of repetitive sequences, including more than
a million short tandem repeats (STRs). While studies of the pathologic consequences of …

Tandem repeats are short DNA sequences that are repeated head-to-tail with a propensity
to be variable. They constitute a significant proportion of the human genome, also occurring …

Short tandem repeats (STRs) are some of the fastest mutating loci in the genome. Tools for
accurately profiling STRs from high-throughput sequencing data have enabled genome …

A problem of 'missing heritability'has been identified following recent genome-wide
association (GWA) studies of single nucleotide polymorphisms (SNPs) associated with …

Genotype-to-phenotype mapping commonly focuses on two major classes of mutations:
single nucleotide polymorphisms (SNPs) and copy number variation (CNV). Here, we …

The contribution of repetitive elements to quantitative human traits is largely unknown. Here
we report a genome-wide survey of the contribution of short tandem repeats (STRs), which …

Copy Number Variations (CNVs) and Single Nucleotide Polymorphisms (SNPs) have been
the major focus of most large-scale comparative genomics studies to date. Here, we discuss …

Tandem repeats represent one of the most abundant class of variations in human genomes,
which are polymorphic by nature and become highly unstable in a length-dependent …