[HTML][HTML] COVID-19: implications for people with Chagas disease

EJ Zaidel, CJ Forsyth, G Novick, R Marcus… - Global Heart, 2020 - ncbi.nlm.nih.gov
As the global COVID-19 pandemic advances, it increasingly impacts those vulnerable
populations who already bear a heavy burden of neglected tropical disease. Chagas …

Chagas disease and SARS-CoV-2 coinfection does not lead to worse in-hospital outcomes

I Molina, MS Marcolino, MC Pires, LEF Ramos… - Scientific Reports, 2021 - nature.com
Chagas disease (CD) continues to be a major public health burden in Latina America.
Information on the interplay between COVID-19 and CD is lacking. Our aim was to assess …

[HTML][HTML] Case report: COVID-19 and Chagas disease in two coinfected patients

RW Alberca, TM Yendo, YÁL Ramos… - The American journal …, 2020 - ncbi.nlm.nih.gov
American trypanosomiasis, also named Chagas disease (CD), is an anthropozoonosis
caused by the protozoan parasite Trypanosoma cruzi. The disease affects millions of people …

Cytokine networks as targets for preventing and controlling Chagas heart disease

CC Koh, EGA Neves, TG de Souza-Silva, AC Carvalho… - Pathogens, 2023 - mdpi.com
Chagas disease, a neglected disease caused by the protozoan Trypanosoma cruzi, is
endemic in 21 Latin American countries, affecting 6–8 million people. Increasing numbers of …

Acute Chagas disease: new global challenges for an old neglected disease

DV Andrade, KJ Gollob, WO Dutra - PLoS neglected tropical …, 2014 - journals.plos.org
Chagas disease is caused by infection with the protozoan Trypanosoma cruzi, and although
over 100 years have passed since the discovery of Chagas disease, it still presents an …

Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation

G Venturini, JM Alvim, K Padilha, CN Toepfer… - Frontiers in cellular …, 2023 - frontiersin.org
Introduction Chagas cardiomyopathy, a disease caused by Trypanosoma cruzi (T. cruzi)
infection, is a major contributor to heart failure in Latin America. There are significant gaps in …

Roadblocks in Chagas disease care in endemic and nonendemic countries: Argentina, Colombia, Spain, and the United States. The NET-Heart project

AF Miranda-Arboleda, EJ Zaidel… - PLoS neglected …, 2021 - journals.plos.org
Background Chagas disease (CD) is endemic in Latin America; however, its spread to
nontropical areas has raised global interest in this condition. Barriers in access to early …

Pathogen diversity, immunity, and the fate of infections: lessons learned from Trypanosoma cruzi human–host interactions

LMD Magalhães, KJ Gollob, B Zingales… - The Lancet …, 2022 - thelancet.com
The complexity of host–pathogen interactions often leads to distinct clinical outcomes upon
infection with different pathogen strains. In this Review, we explore the interactions between …

Chagas cardiomyopathy: an update of current clinical knowledge and management: a scientific statement from the American Heart Association

MCP Nunes, A Beaton, H Acquatella, C Bern… - Circulation, 2018 - Am Heart Assoc
Background: Chagas disease, resulting from the protozoan Trypanosoma cruzi, is an
important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally …

[HTML][HTML] WHF IASC roadmap on Chagas disease

LE Echeverría, R Marcus, G Novick, S Sosa-Estani… - Global …, 2020 - ncbi.nlm.nih.gov
Background: Chagas Disease is a neglected tropical disease caused by the protozoan
Trypanosoma cruzi, with some of the most serious manifestations affecting the …