Tailoring the porosity and pore size of electrospun synthetic human elastin scaffolds for dermal tissue engineering

J Rnjak-Kovacina, SG Wise, Z Li, PKM Maitz, CJ Young… - Biomaterials, 2011 - Elsevier
We obtained low and high porosity synthetic human elastin scaffolds by adapting low (1
mL/h) and high (3 mL/h) flow rates respectively during electrospinning. Physical, mechanical …

Electrospun synthetic human elastin: collagen composite scaffolds for dermal tissue engineering

J Rnjak-Kovacina, SG Wise, Z Li, PKM Maitz, CJ Young… - Acta biomaterialia, 2012 - Elsevier
We present an electrospun synthetic human elastin: collagen composite scaffold aimed at
dermal tissue engineering. The panel of electrospun human tropoelastin and ovine type I …

Electrospun protein fibers as matrices for tissue engineering

M Li, MJ Mondrinos, MR Gandhi, FK Ko, AS Weiss… - Biomaterials, 2005 - Elsevier
Electrospinning has recently emerged as a leading technique for generating biomimetic
scaffolds made of synthetic and natural polymers for tissue engineering applications. In this …

Increasing the pore size of electrospun scaffolds

J Rnjak-Kovacina, AS Weiss - Tissue Engineering Part B: Reviews, 2011 - liebertpub.com
Electrospinning has gained much attention in the past decade as an effective means of
generating nano-to micro-scale polymer fibers that resemble native extracellular matrix …

Electrospun fibrous mats with high porosity as potential scaffolds for skin tissue engineering

X Zhu, W Cui, X Li, Y Jin - Biomacromolecules, 2008 - ACS Publications
Diffusional limitations of mass transport have adverse effects on engineering tissues that
normally have high vascularity and cellularity. The current electrospinning method is not …

Primary human dermal fibroblast interactions with open weave three-dimensional scaffolds prepared from synthetic human elastin

J Rnjak, Z Li, PKM Maitz, SG Wise, AS Weiss - Biomaterials, 2009 - Elsevier
We present an elastic, fibrous human protein-based and cell-interactive dermal substitute
scaffold based on synthetic human elastin. Recombinant human tropoelastin promoted …

Applications of electrospun scaffolds with enlarged pores in tissue engineering

Y Zhang, M Zhang, D Cheng, S Xu, C Du, L Xie… - Biomaterials …, 2022 - pubs.rsc.org
Despite electrospinning having multiple advantages over other methods such as creating
materials with a superfine fiber diameter, high specific surface area, and good mechanical …

Strategies to tune electrospun scaffold porosity for effective cell response in tissue engineering

JM Ameer, AK Pr, N Kasoju - Journal of functional biomaterials, 2019 - mdpi.com
Tissue engineering aims to develop artificial human tissues by culturing cells on a scaffold in
the presence of biochemical cues. Properties of scaffold such as architecture and …

Electrospun collagen nanofibers and their applications in skin tissue engineering

JX Law, LL Liau, A Saim, Y Yang, R Idrus - Tissue engineering and …, 2017 - Springer
Electrospinning is a simple and versatile technique to fabricate continuous fibers with
diameter ranging from micrometers to a few nanometers. To date, the number of polymers …

Dermal fibroblast infiltration of poly (ε-caprolactone) scaffolds fabricated by melt electrospinning in a direct writing mode

BL Farrugia, TD Brown, Z Upton, DW Hutmacher… - …, 2013 - iopscience.iop.org
Melt electrospinning in a direct writing mode is a recent additive manufacturing approach to
fabricate porous scaffolds for tissue engineering applications. In this study, we describe …