Neural versus alternative integrative systems: molecular insights into origins of neurotransmitters

LL Moroz, DY Romanova… - … Transactions of the …, 2021 - royalsocietypublishing.org
Transmitter signalling is the universal chemical language of any nervous system, but little is
known about its early evolution. Here, we summarize data about the distribution and …

Independent origins of neurons and synapses: insights from ctenophores

LL Moroz, AB Kohn - … Transactions of the Royal Society B …, 2016 - royalsocietypublishing.org
There is more than one way to develop neuronal complexity, and animals frequently use
different molecular toolkits to achieve similar functional outcomes. Genomics and …

[HTML][HTML] The evolutionary assembly of neuronal machinery

D Arendt - Current Biology, 2020 - cell.com
Neurons are highly specialized cells equipped with a sophisticated molecular machinery for
the reception, integration, conduction and distribution of information. The evolutionary origin …

The chemical brain hypothesis for the origin of nervous systems

G Jékely - … Transactions of the Royal Society B, 2021 - royalsocietypublishing.org
In nervous systems, there are two main modes of transmission for the propagation of activity
between cells. Synaptic transmission relies on close contact at chemical or electrical …

[HTML][HTML] Alternative neural systems: what is a neuron?(ctenophores, sponges and placozoans)

LL Moroz, DY Romanova - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
How to make a neuron, a synapse, and a neural circuit? Is there only one 'design'for a
neural architecture with a universally shared genomic blueprint across species? The brief …

On the independent origins of complex brains and neurons

LL Moroz - Brain Behavior and Evolution, 2009 - karger.com
Abstract Analysis of the origin and evolution of neurons is crucial for revealing principles of
organization of neural circuits with unexpected implications for genomic sciences …

[HTML][HTML] Stepwise emergence of the neuronal gene expression program in early animal evolution

SR Najle, X Grau-Bové, A Elek, C Navarrete… - Cell, 2023 - cell.com
The assembly of the neuronal and other major cell type programs occurred early in animal
evolution. We can reconstruct this process by studying non-bilaterians like placozoans …

Evolution of synapses and neurotransmitter systems: The divide-and-conquer model for early neural cell-type evolution

P Burkhardt, G Jékely - Current Opinion in Neurobiology, 2021 - Elsevier
Nervous systems evolved around 560 million years ago to coordinate and empower animal
bodies. Ctenophores–one of the earliest-branching lineages—are thought to share a few …

Evolution of central neural circuits: state of the art and perspectives

RJV Roberts, S Pop, LL Prieto-Godino - Nature Reviews Neuroscience, 2022 - nature.com
The wide variety of animal behaviours that can be observed today arose through the
evolution of their underlying neural circuits. Advances in understanding the mechanisms …

Refocusing neuroscience: moving away from mental categories and towards complex behaviours

L Pessoa, L Medina, E Desfilis - … Transactions of the …, 2022 - royalsocietypublishing.org
Mental terms—such as perception, cognition, action, emotion, as well as attention, memory,
decision-making—are epistemically sterile. We support our thesis based on extensive …