[HTML][HTML] Mycobacterium tuberculosis and whole-genome sequencing: how close are we to unleashing its full potential?

G Satta, M Lipman, GP Smith, C Arnold, OM Kon… - Clinical Microbiology …, 2018 - Elsevier
Background Nearly two decades after completion of the genome sequence of
Mycobacterium tuberculosis (MTB), and with the advent of next generation sequencing …

Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues

CJ Meehan, GA Goig, TA Kohl, L Verboven… - NATURE reviews …, 2019 - nature.com
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has rapidly progressed
from a research tool to a clinical application for the diagnosis and management of …

[HTML][HTML] Mycobacterium tuberculosis and whole genome sequencing: a practical guide and online tools available for the clinical microbiologist

G Satta, A Atzeni, TD McHugh - Clinical Microbiology and Infection, 2017 - Elsevier
Whole genome sequencing (WGS) has the potential to revolutionize the diagnosis of
Mycobacterium tuberculosis infection but the lack of bioinformatic expertise among clinical …

Mycobacterium tuberculosis–heterogeneity revealed through whole genome sequencing

C Ford, K Yusim, T Ioerger, S Feng, M Chase… - Tuberculosis, 2012 - Elsevier
The emergence of whole genome sequencing (WGS) technologies as primary research
tools has allowed for the detection of genetic diversity in Mycobacterium tuberculosis (Mtb) …

Comprehensive whole-genome sequencing and reporting of drug resistance profiles on clinical cases of Mycobacterium tuberculosis in New York State

J Shea, TA Halse, P Lapierre, M Shudt… - Journal of clinical …, 2017 - Am Soc Microbiol
Whole-genome sequencing (WGS) is a newer alternative for tuberculosis (TB) diagnostics
and is capable of providing rapid drug resistance profiles while performing species …

Clinical use of whole genome sequencing for Mycobacterium tuberculosis

AA Witney, CA Cosgrove, A Arnold, J Hinds, NG Stoker… - BMC medicine, 2016 - Springer
Drug-resistant tuberculosis (TB) remains a major challenge to global health and to
healthcare in the UK. In 2014, a total of 6,520 cases of TB were recorded in England, of …

SAM-TB: a whole genome sequencing data analysis website for detection of Mycobacterium tuberculosis drug resistance and transmission

T Yang, M Gan, Q Liu, W Liang, Q Tang… - Briefings in …, 2022 - academic.oup.com
Whole genome sequencing (WGS) can provide insight into drug-resistance, transmission
chains and the identification of outbreaks, but data analysis remains an obstacle to its …

Whole genome sequencing of Mycobacterium tuberculosis

AM Cabibbe, TM Walker, S Niemann… - European Respiratory …, 2018 - Eur Respiratory Soc
Whole genome sequencing of Mycobacterium tuberculosis | European Respiratory Society Skip
to main content Main menu Home Current issue ERJ Early View Past issues ERS Guidelines …

Deciphering drug resistance in Mycobacterium tuberculosis using whole-genome sequencing: progress, promise, and challenges

KA Cohen, AL Manson, CA Desjardins, T Abeel… - Genome medicine, 2019 - Springer
Tuberculosis (TB) is a global infectious threat that is intensified by an increasing incidence of
highly drug-resistant disease. Whole-genome sequencing (WGS) studies of Mycobacterium …

Whole-genome sequencing of Mycobacterium tuberculosis directly from clinical samples for high-resolution genomic epidemiology and drug resistance surveillance …

GA Goig, I Cancino-Muñoz, M Torres-Puente… - The Lancet …, 2020 - thelancet.com
Background Direct whole-genome sequencing of Mycobacterium tuberculosis from clinical
specimens will be a major breakthrough in tuberculosis diagnosis and control. To date …