Injectable hydrogels have been studied as drug delivery systems because of their minimal
invasiveness and sustained drug release properties. Pluronic F127, consisting of poly …

In this study, a novel glycol chitosan-Pluronic F127 conjugate (GC-PF127) was produced by
adding a carboxyl group to the end of Pluronic F127 followed by an amidation reaction …

In this study, a pH-responsive hydrogel consisting of a 4-arm poly (ethylene glycol)-block-
poly (L-glutamic acid)(4a-PEG-PLG) copolymer was developed and used for the controlled …

Background Most conventional methods for delivering chemotherapeutic agents fail to
achieve therapeutic concentrations of drugs, despite reaching toxic systemic levels. Novel …

Using hydrogels to control the long-term release of protein remains challenging, especially
for in-situ forming formulations. The uncontrollable burst release in the initial phase, the …

Supramolecular hydrogels, which are held together by noncovalent bonds and show
responses to external stimuli, are of great interest in therapeutic delivery and tissue …

Injectable sol–gel transition hydrogels based on thermo-sensitive polymers are of great
interest as potential biomaterials for sustained delivery of therapeutic molecules. A novel …

Poly (ethylene glycol)(PEG) hydrogels are widely used to deliver therapeutic biomolecules,
due to high hydrophilicity, tunable physicochemical properties, and anti-fouling properties …

Protein therapeutics represent a rapidly growing class of pharmaceutical agents that hold
great promise for the treatment of various diseases such as cancer and autoimmune …

Abstract Pluronic F-127 (PF127) is a thermosensitive polymer that has been widely
recognized as a potential candidate for various bio-applications. However, in hydrogel form …