Background Psychological problems are associated with IBS but the strength of this
association is unclear. Aim To assess co‐prescribing of antispasmodic and CNS‐acting …

Background Irritable bowel syndrome (IBS) is the most common functional gastrointestinal
(GI) disorder observed in patients who visit general practitioners for GI-related complaints. A …

Methods The prospective, population-based Lifelines cohort study includes 132 922 adults
without prior IBS or taking IBS medication at baseline. Baseline data included socio …

Aims The aims of this study were to better define the relationship between irritable bowel
syndrome (IBS) and psychiatric disorders and to examine the efficacy of paroxetine in the …

METHODS: We collected complete demographic, symptom, and psychological comorbidity
data (anxiety, depression, somatic symptom disorder, perceived stress, and gastrointestinal …

Background Irritable bowel syndrome is a common problem known to have a complex
relationship with psychological disorders and other physical symptoms. Little information …

Objective: Although irritable bowel syndrome (IBS) is highly comorbid with depressive and
anxiety disorders, information on the clinical implications of this comorbidity is limited. We …

Objective: Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder.
Evidence for treatment of the condition with antidepressants and psychological therapies is …

The understanding of irritable bowel syndrome (IBS) has evolved over the last 30 years from
a simple and reductionistic biomedical view to a primarily physiological or motility-focused …

Background The prevalence of irritable bowel syndrome (IBS) is now known to be similar in
various geographical regions, but there has been no study directly comparing characteristics …