DNA methylation directs microRNA biogenesis in mammalian cells
MicroRNA (miRNA) biogenesis initiates co-transcriptionally, but how the Microprocessor
machinery pinpoints the locations of short precursor miRNA sequences within long flanking …
machinery pinpoints the locations of short precursor miRNA sequences within long flanking …
Methylation of human microRNA genes in normal and neoplastic cells
B Weber, C Stresemann, B Brueckner, F Lyko - Cell cycle, 2007 - Taylor & Francis
MicroRNAs (miRNAs) are small RNA molecules that control gene expression by inhibition of
protein translation or by degradation of cognate target mRNAs. Even though strict …
protein translation or by degradation of cognate target mRNAs. Even though strict …
Mutual regulation of microRNAs and DNA methylation in human cancers
S Wang, W Wu, FX Claret - Epigenetics, 2017 - Taylor & Francis
ABSTRACT microRNAs (miRNAs) and DNA methylation are the 2 epigenetic modifications
that have emerged in recent years as the most critical players in the regulation of gene …
that have emerged in recent years as the most critical players in the regulation of gene …
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
L Sinkkonen, T Hugenschmidt, P Berninger… - Nature structural & …, 2008 - nature.com
Loss of microRNA (miRNA) pathway components negatively affects differentiation of
embryonic stem (ES) cells, but the underlying molecular mechanisms remain poorly defined …
embryonic stem (ES) cells, but the underlying molecular mechanisms remain poorly defined …
Extensive post-transcriptional regulation of microRNAs and its implications for cancer
JM Thomson, M Newman, JS Parker… - Genes & …, 2006 - genesdev.cshlp.org
MicroRNAs (miRNAs) are short, noncoding RNAs that post-transcriptionally regulate gene
expression. While hundreds of mammalian miRNA genes have been identified, little is …
expression. While hundreds of mammalian miRNA genes have been identified, little is …
MicroRNAs and epigenetics
F Sato, S Tsuchiya, SJ Meltzer, K Shimizu - The FEBS journal, 2011 - Wiley Online Library
MicroRNAs (miRNAs) comprise species of short noncoding RNA that regulate gene
expression post‐transcriptionally. Recent studies have demonstrated that epigenetic …
expression post‐transcriptionally. Recent studies have demonstrated that epigenetic …
Impaired microRNA processing enhances cellular transformation and tumorigenesis
MicroRNAs (miRNAs) are a new class of small noncoding RNAs that post-transcriptionally
regulate the expression of target mRNA transcripts. Many of these target mRNA transcripts …
regulate the expression of target mRNA transcripts. Many of these target mRNA transcripts …
[HTML][HTML] Human RNA methyltransferase BCDIN3D regulates microRNA processing
MicroRNAs (miRNAs) regulate key biological processes and their aberrant expression may
lead to cancer. The primary transcript of canonical miRNAs is sequentially cleaved by the …
lead to cancer. The primary transcript of canonical miRNAs is sequentially cleaved by the …
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
Dicer initiates RNA interference by generating small RNAs involved in various silencing
pathways. Dicer participates in centromeric silencing, but its role in the epigenetic regulation …
pathways. Dicer participates in centromeric silencing, but its role in the epigenetic regulation …