[PDF][PDF] P-Selectin and Immune Activation in HIV: Clinical Implications
P-Selectin, a pivotal cell adhesion molecule expressed on activated endothelial cells and
platelets, plays a critical role in immune activation and inflammation. In the context of human …
platelets, plays a critical role in immune activation and inflammation. In the context of human …
[PDF][PDF] P-Selectin and Platelet Activation in HIV: Implications for Antiviral Therapy
Platelet activation and dysregulation of cell adhesion molecules, particularly P-Selectin, play
pivotal roles in the pathogenesis of human immunodeficiency virus (HIV) infection …
pivotal roles in the pathogenesis of human immunodeficiency virus (HIV) infection …
[PDF][PDF] P-Selectin Expression in HIV-Associated Coagulopathy: Implications for Treatment
HIV infection is associated with a heightened risk of coagulopathy, encompassing
thrombosis, hemorrhage, and endothelial dysfunction, which significantly impact disease …
thrombosis, hemorrhage, and endothelial dysfunction, which significantly impact disease …
[PDF][PDF] L-selectin and HIV-Induced Immune Cell Trafficking: Implications for Pathogenesis and Therapeutic Strategies
HIV infection is characterized by dysregulated immune cell trafficking, contributing to chronic
immune activation, inflammation, and disease progression. L-selectin, a key adhesion …
immune activation, inflammation, and disease progression. L-selectin, a key adhesion …
[PDF][PDF] Exploring the Role of L-selectin in HIV-related Immune Exhaustion: Insights and Therapeutic Implications
HIV infection leads to progressive immune dysfunction characterized by T cell exhaustion, a
state of functional impairment and loss of effector functions. L-selectin, a key adhesion …
state of functional impairment and loss of effector functions. L-selectin, a key adhesion …
[PDF][PDF] Modulation of L-selectin Expression in Tuberculosis-HIV Coinfection: Implications for Disease Control
Tuberculosis (TB) and human immunodeficiency virus (HIV) coinfection presents a complex
challenge in global health, characterized by heightened disease severity and therapeutic …
challenge in global health, characterized by heightened disease severity and therapeutic …
[PDF][PDF] Understanding Immune Cell Trafficking in Tuberculosis-HIV Coinfection: The Role of L-selectin Pathways
Tuberculosis (TB) and human immunodeficiency virus (HIV) coinfection pose significant
challenges to global health, with dysregulated immune cell trafficking contributing to disease …
challenges to global health, with dysregulated immune cell trafficking contributing to disease …
[HTML][HTML] The role of platelet-activating factor in chronic inflammation, immune activation, and comorbidities associated with HIV infection
T Kelesidis, V Papakonstantinou, P Detopoulou… - AIDS …, 2015 - ncbi.nlm.nih.gov
With the advent of highly effective antiretroviral therapy, cardiovascular disease has become
an important cause of morbidity and mortality among people with treated HIV-1, but the …
an important cause of morbidity and mortality among people with treated HIV-1, but the …
Increased platelet and microparticle activation in HIV infection: upregulation of P-selectin and tissue factor expression
Objective: HIV-1–infected patients have an increased risk for atherothrombosis and
cardiovascular disease, but the mechanism behind these risks is poorly understood. We …
cardiovascular disease, but the mechanism behind these risks is poorly understood. We …
[PDF][PDF] Programmed Cell Death Protein 1 (PD-1) Signaling in HIV-Associated Cardiovascular Disease: Mechanisms and Therapeutic Implications
Cardiovascular disease (CVD) remains a significant cause of morbidity and mortality in
individuals living with HIV/AIDS, despite effective antiretroviral therapy (ART). Emerging …
individuals living with HIV/AIDS, despite effective antiretroviral therapy (ART). Emerging …