Microglia are activated in many neurological diseases and have been suggested to play an
important role in the development of affective disorders including major depression. To …

Major depressive disorder is a highly debilitating psychiatric disorder involving the
dysfunction of different cell types in the brain. Microglia are the predominant resident …

Chronic stress is a major risk factor for various psychiatric diseases, including depression; it
triggers various cellular and structural changes, resulting in the alteration of neurocircuitry …

Major depressive disorder (MDD) is a debilitating neuropsychological disorder, which has
caused serious health and socio-economic burdens worldwide. A growing body of evidence …

Increasing evidence supports the notion that neuroinflammation plays a critical role in the
etiology of major depressive disorder (MDD), at least in a subset of patients. By virtue of their …

Depression has been widely accepted as a major psychiatric disease affecting nearly 350
million people worldwide. Research focus is now shifting from studying the extrinsic and …

Major depressive disorder (MDD) is a common emotional cognitive disorder that seriously
affects people's physical and mental health and their quality of life. Due to its clinical and …

Major depressive disorder (MDD) is a prevalent psychiatric disease that involves
malfunctions of different cell types in the brain. Accumulating studies started to reveal that …

Microglia, the brain's resident immune cells, are phagocytes of the macrophage lineage that
have a key role in responding to inflammation and immune challenge in the brain. More …

Microglia are the major immune cells in the central nervous system and play a key role in the
normal function of the brain. Microglia exhibit functional diversity, and they control the …