The brain endothelial cell (BEC) glycocalyx (ecGCx) is a BEC surface coating consisting of a
complex interwoven polysaccharide (sweet husk) mesh-like network of membrane-bound …

Astrocytes (ACs) are the most abundant cells in the brain and, importantly, are the master
connecting and communicating cells that provide structural and functional support for brain …

The socio-economic impact of diseases associated with cognitive impairment is increasing.
According to the Alzheimer's Society there are over 850,000 people with dementia in the UK …

The blood‐brain barrier is a dynamic and complex neurovascular unit that protects neurons
from somatic circulatory factors as well as regulates the internal environmental stability of the …

The blood–brain barrier (BBB) is a vital interface that supports normal brain functions.
Endothelial cells (ECs) are the main component of the BBB and are highly specialized to …

Embryonic genetic mechanisms are present in the brain and ready to be placed into action
upon cellular injury, termed the response to injury wound-healing (RTIWH) mechanism …

The integrity of the endothelial glycocalyx (eGCX), a mixture of carbohydrates attached to
proteins expressed on the surface of blood vessel endothelial cells (EC), is critical for the …

Expressed on the endothelial cell (EC) surface of blood vessels, the glycocalyx (GCX), a
mixture of carbohydrates attached to proteins, regulates the access of cells and molecules in …

Background/Aims: Endothelial glycocalyx refers to the proteoglycan or glycoprotein layer of
vessel walls and has critical physiological functions. Cerebral glycocalyx may have …

According to the “obesity paradox,” for severe conditions, individuals with obesity may be
associated with a higher survival rate than those who are lean. However, the physiological …