Corneal endothelial disorders collectively represent a significant healthcare burden in most
developed nations, and corneal transplantation is currently the only treatment available for …

Decompensation of the corneal endothelium causes severe visual impairments that lead to
blindness. Although corneal transplantation is a well-known effective therapy for corneal …

Corneal transplantation is the only available treatment to restore vision in patients suffering
from endotheliopathies. Tissue engineering offers new alternatives for the replacement of …

The state of the art therapy for treating corneal endothelial disease is transplantation.
Advances in the reproducibility and accessibility of surgical techniques are increasing the …

When corneal endothelial cells (CECs) are diseased or injured, corneal endothelium can be
surgically removed and tissue from a deceased donor can replace the original endothelium …

Human corneal endothelial cells are notorious for their restricted proliferative ability in vivo
and in vitro. Hence, injury or dysfunction of these cells may easily result in blindness …

Corneal endothelium is a single layer of specialized cells that lines the posterior surface of
cornea and maintains corneal hydration and corneal transparency essential for vision …

Human corneal endothelial cells (HCEC) play a pivotal role in maintaining corneal
transparency. Unlike in other species, HCEC are notorious for their limited proliferative …

Corneal transplantation is the only treatment for corneal endothelial blindness. However,
there is an urgent need to find substitutes for corneal endothelium grafts due to the global …

Human corneal endothelial cells have two major functions: barrier function mediated by
proteins such as ZO-1 and pump function mediated by Na-K-ATPase which help to maintain …