Salvinorin A is a naturally occurring hallucinogenic diterpenoid from the plant Salvia
divinorum that selectively and potently activates κ-opioid receptors (KORs). Salvinorin A is …

Salvinorin A, the active component of the hallucinogenic sage Salvia divinorum, is an
apparently selective and highly potent κ-opioid receptor (KOR) agonist. Salvinorin A is …

Salvinorin A, the most potent naturally occurring hallucinogen, has attracted an increasing
amount of attention since the κ-opioid receptor (KOR) was identified as its principal …

The diterpene salvinorin A from Salvia divinorum has recently been reported to be a high-
affinity and selective κ-opioid receptor agonist (Roth et al., 2002). Salvinorin A and selected …

The neoclerodane diterpenoid salvinorin A is a major secondary metabolite isolated from
the psychoactive plant Salvia divinorum. Salvinorin A has been shown to have high affinity …

The plant metabolite salvinorin A potently and selectively agonizes the human kappa-opioid
receptor, an emerging target for next-generation analgesics. Here we review analogs of the …

The neoclerodane diterpene salvinorin A, found in the leaves of Salvia divinorum, is a potent
κ-opioid receptor agonist, making it an attractive scaffold for development into a treatment for …

Salvia divinorum is a natural occurring hallucinogen that is traditionally used by the Mazatec
Indians of central Mexico. The diterpene salvinorin A was identified as an active component …

Data from clinical and preclinical studies converge implicating the plant-derived
hallucinogen salvinorin A as an important pharmacologic tool; this psychoactive compound …

κ-opioid receptors (KORs) represent the principal site of action of dynorphin and related
neuropeptides. Recently, Salvinorin A—a naturally occurring neoclerodane diterpene …