Metabolic Profiling to Assess Response to Targeted and Immune Therapy in Melanoma
There is currently no consensus to determine which advanced melanoma patients will
benefit from targeted therapy, immunotherapy, or a combination of both, highlighting the …
benefit from targeted therapy, immunotherapy, or a combination of both, highlighting the …
Melanoma metabolism: cell survival and resistance to therapy
Cutaneous melanoma is one of the most aggressive types of cancer, presenting the highest
potential to form metastases, both locally and distally, which are associated with high death …
potential to form metastases, both locally and distally, which are associated with high death …
Metabolic interplay between the immune system and melanoma cells: therapeutic implications
Malignant melanoma represents the most fatal skin cancer due to its aggressive biological
behavior and high metastatic potential. Treatment strategies for advanced disease have …
behavior and high metastatic potential. Treatment strategies for advanced disease have …
Metabolic Imaging Biomarkers of Response to Signaling Inhibition Therapy in Melanoma
PK Gupta, S Orlovskiy, F Arias-Mendoza, DS Nelson… - Cancers, 2024 - mdpi.com
Simple Summary In vivo, 1H and 31P magnetic resonance spectroscopy were used to study
human melanoma models to monitor the metabolic effects of dabrafenib therapy, an inhibitor …
human melanoma models to monitor the metabolic effects of dabrafenib therapy, an inhibitor …
[HTML][HTML] 1H and 31P Magnetic Resonance Spectroscopic Metabolomic Imaging: Assessing Mitogen-Activated Protein Kinase Inhibition in Melanoma
PK Gupta, S Orlovskiy, F Arias-Mendoza, DS Nelson… - Cells, 2024 - mdpi.com
The MAPK signaling pathway with BRAF mutations has been shown to drive the
pathogenesis of 40–60% of melanomas. Inhibitors of this pathway's BRAF and MEK …
pathogenesis of 40–60% of melanomas. Inhibitors of this pathway's BRAF and MEK …
Metabolic traits in cutaneous melanoma
M Neagu - Frontiers in oncology, 2020 - frontiersin.org
Tumor microenvironment is a network of complex cellular and molecular systems where
cells will gain specific phenotypes and specific functions that would drive tumorigenesis. In …
cells will gain specific phenotypes and specific functions that would drive tumorigenesis. In …
Molecular probes for malignant melanoma imaging
G Ren, Y Pan, Z Cheng - Current pharmaceutical …, 2010 - ingentaconnect.com
Malignant melanoma represents a serious public health problem and is a deadly disease
when it is diagnosed at late stage. Though 18F-fluorodeoxyglucose (18F-FDG) positron …
when it is diagnosed at late stage. Though 18F-fluorodeoxyglucose (18F-FDG) positron …
Metabolism heterogeneity in melanoma fuels deactivation of immunotherapy: predict before protect
X Zhang, Z Tai, F Miao, H Huang, Q Zhu, L Bao… - Frontiers in …, 2022 - frontiersin.org
Malignant melanoma is widely acknowledged as the most lethal skin malignancy. The
metabolic reprogramming in melanoma leads to alterations in glycolysis and oxidative …
metabolic reprogramming in melanoma leads to alterations in glycolysis and oxidative …
Future perspectives in melanoma research: meeting report from the" Melanoma Bridge", Napoli, December 5th-8th 2013
Abstract The fourth" Melanoma Bridge Meeting" took place in Naples, December 5 to 8 th,
2013. The four topics discussed at this meeting were: Diagnosis and New Procedures …
2013. The four topics discussed at this meeting were: Diagnosis and New Procedures …
[HTML][HTML] Predictive and on-treatment monitoring biomarkers in advanced melanoma: Moving toward personalized medicine
A Tarhini, RR Kudchadkar - Cancer treatment reviews, 2018 - Elsevier
The treatment armamentarium for patients with metastatic melanoma has increased
substantially over the past decade with the regulatory approval of targeted BRAF+ MEK …
substantially over the past decade with the regulatory approval of targeted BRAF+ MEK …