[HTML][HTML] Neurodynamic treatment promotes mechanical pain modulation in sensory neurons and nerve regeneration in rats

G Carta, BE Fornasari, F Fregnan, G Ronchi… - Biomedicines, 2022 - mdpi.com
Background: Somatic nerve injuries are a rising problem leading to disability associated with
neuropathic pain commonly reported as mechanical allodynia (MA) and hyperalgesia …

[HTML][HTML] The neurodynamic treatment induces biological changes in sensory and motor neurons in vitro

G Carta, G Gambarotta, BE Fornasari, L Muratori… - Scientific Reports, 2021 - nature.com
Nerves are subjected to tensile forces in various paradigms such as injury and regeneration,
joint movement, and rehabilitation treatments, as in the case of neurodynamic treatment …

Analgesic effects of tonic and burst dorsal root ganglion stimulation in rats with painful tibial nerve injury

G Yu, I Segel, H Tran, HJ Park, E Ross… - … : Technology at the …, 2022 - Elsevier
Objectives Dorsal root ganglion (DRG) stimulation is effective in treating chronic pain. While
burst stimulation has been proven to enhance the therapeutic efficacy in spinal cord …

Neural mobilization reverses behavioral and cellular changes that characterize neuropathic pain in rats

FM Santos, JT Silva, AC Giardini, PA Rocha… - Molecular …, 2012 - journals.sagepub.com
Background: The neural mobilization technique is a noninvasive method that has proved
clinically effective in reducing pain sensitivity and consequently in improving quality of life …

[HTML][HTML] Dorsal root ganglionic field stimulation relieves spontaneous and induced neuropathic pain in rats

B Pan, H Yu, GJ Fischer, JM Kramer, QH Hogan - The Journal of Pain, 2016 - Elsevier
Dorsal root ganglion (DRG) electrical stimulation (ganglionic field stimulation [GFS]) is
effective in relieving clinical pain, but its mechanism is unknown. We therefore developed a …

[HTML][HTML] Peripheral and central changes induced by neural mobilization in animal models of neuropathic pain: a systematic review

F Salniccia, S de Vidania, L Martinez-Caro - Frontiers in Neurology, 2024 - frontiersin.org
Introduction Neural mobilization (NM) is a physiotherapy technique involving the passive
mobilization of limb nerve structures with the aim to attempt to restore normal movement and …

[HTML][HTML] Abnormal reinnervation of denervated areas following nerve injury facilitates neuropathic pain

H Leibovich, N Buzaglo, S Tsuriel, L Peretz, Y Caspi… - Cells, 2020 - mdpi.com
An injury to peripheral nerves leads to skin denervation, which often is followed by
increased pain sensitivity of the denervated areas and the development of neuropathic pain …

Axotomy-induced up-regulation of tumor necrosis factor-alpha in the dorsal root ganglia

P Miao, K Madec, Y Gong, H Shen… - Neurological …, 2008 - Taylor & Francis
Objectives: Neuropathic pain is a chronic pain syndrome associated with drug, injury or
disease-induced damage or destruction of sensory afferent fibers of the dorsal root ganglia …

Non-pharmacological treatment affects neuropeptide expression in neuropathic pain model

FM Santos, JT Silva, IRC Rocha, DO Martins, M Chacur - Brain research, 2018 - Elsevier
Chronic constriction injury (CCI) of the sciatic nerve elicits changes in neuropeptide
expression on the dorsal root ganglia (DRG). The neural mobilization (NM) technique is a …

Time course of inflammation in dorsal root ganglia correlates with differential reversibility of mechanical allodynia

M Noh, B Mikler, T Joy, PA Smith - Neuroscience, 2020 - Elsevier
Some individuals recover from the pain of nerve trauma within 12 months or less whereas
others experience life-long intractable pain. This transition between reversible pain and the …