Molecular Docking Studies and Anti-Alzheimer's Potential of Isolated Compounds from Tinospora cordifolia
Inhibition of acetylcholinesterase (AChE) is a promising strategy for the management of
Alzheimer's disease (AD). Prolyl endopeptidase (PEP) is a post-proline cleaving enzyme …
Alzheimer's disease (AD). Prolyl endopeptidase (PEP) is a post-proline cleaving enzyme …
[HTML][HTML] Cholinesterase inhibitory activity of tinosporide and 8-hydroxytinosporide isolated from Tinospora cordifolia: In vitro and in silico studies targeting …
Tinosporide and 8-hydroxytinosporide isolated from Tinospora cordifolia were evaluated for
acetylcholinesterase (AChE) and butylcholinesterase (BuChE) inhibitory activities. The …
acetylcholinesterase (AChE) and butylcholinesterase (BuChE) inhibitory activities. The …
[PDF][PDF] Insilco identification of suitable acetuylcholinesterase inhibitors from morinda citrifolia linn. with reference to alzheimer's disease
K Praveen, K Yellamma - International Journal of Pharmaceutical …, 2014 - researchgate.net
Alzheimer's disease, the most common form of dementia accounting for about 50-60% of the
overall cases among persons over 65 years of age is characterized by the progressive …
overall cases among persons over 65 years of age is characterized by the progressive …
In silico molecular docking and dynamic simulation of anti-cholinesterase compounds from the extract of Catunaregam spinosa for possible treatment of Alzheimer's …
S Thandivel, P Rajan, T Gunasekar, A Arjunan, S Khute… - Heliyon, 2024 - cell.com
Abstract Alzheimer's disease (AD), is characterized by a progressive loss of cognitive
abilities as well as behavioral symptoms including disorientation, trouble solving problems …
abilities as well as behavioral symptoms including disorientation, trouble solving problems …
Lepidine b from lepidium sativum seeds as multi-functional anti-Alzheimer's disease agent: In vitro and in silico studies
Objective: The present study is carried out to screen the anticholinesterase effect of the total
alkaloids of L. sativum seeds and other plants, and studied the ability of Lepidine B & E to …
alkaloids of L. sativum seeds and other plants, and studied the ability of Lepidine B & E to …
[PDF][PDF] Molecular docking studies of flavonoids from Andrographis paniculata as potential acetylcholinesterase, butyrylcholinesterase and monoamine oxidase …
Neurodegenerative diseases have been characterized by loss of neuron structures as well
as their functions. This study was designed to assess molecular docking of flavonoids from …
as their functions. This study was designed to assess molecular docking of flavonoids from …
Anti-acetylcholinesterase activities of mono-herbal extracts and exhibited synergistic effects of the phytoconstituents: A biochemical and computational study
Alzheimer's disease (AD), a neurodegenerative disease, is the most common form of
dementia. Inhibition of acetylcholinesterase (AChE) is a common strategy for the treatment of …
dementia. Inhibition of acetylcholinesterase (AChE) is a common strategy for the treatment of …
[HTML][HTML] Molecular docking study of certain plant alkaloid derivatives as inhibitors of various drug targets of Alzheimer's disease
R Ganesh, I Kannan - Biomedical and Pharmacology …, 2017 - biomedpharmajournal.org
Alzheimer's disease is a deadly form of dementia, and can greatly affect the way a person
can think and behave. It is the sixth leading cause of death in the US alone. Clusters of Beta …
can think and behave. It is the sixth leading cause of death in the US alone. Clusters of Beta …
[PDF][PDF] Molecular docking studies on the therapeutic targets of Alzheimer's disease (AChE and BChE) using natural bioactive alkaloids
P Jyothi, K Yellamma - Int J Pharm Pharm Sci, 2016 - academia.edu
Objective: Alzheimer's disease (AD), a progressive neurodegenerative disorder with many
cognitive and neuropsychiatric symptoms, is biochemically characterized by a significant …
cognitive and neuropsychiatric symptoms, is biochemically characterized by a significant …
Molecular docking study on columbin isolated from Tinospora cordifolia as a cholinesterase inhibitor
Purpose: To investigate the acetylcholinesterase (AChE) inhibitory potential of columbin and
also to assess its binding affinity against AChE protein. Methods: Crystals of columbin were …
also to assess its binding affinity against AChE protein. Methods: Crystals of columbin were …