The metabolic associated fatty liver disease (MAFLD) is a public health challenge, leading to
a global increase in chronic liver disease. The respiratory exposure of silica nanoparticles …

Silica nanoparticles (SiNPs) are derived from manufactured materials and the natural
environment, and they cause detrimental effects on human health via various exposure …

Background As a promising nanocarrier in biomedical fields, silica nanoparticles (SiNPs)
could transfer from the circulatory system to multiple organs. Among these, blood–liver …

Amorphous silica nanoparticles (SiNPs) have been widely used and mass-producted due to
its unique properties. With the life cycle of SiNPs-based products, SiNPs are further released …

Silica nanoparticles (SiNPs) have become one of the most widely studied nanoparticles in
nanotechnology for environmental health and safety. Although many studies have devoted …

The liver is one of the target organs of silica nanoparticles (SiO2 NPs) but the toxic
mechanism on the liver still remains unclear. This study aimed to explore the hepatic toxicity …

Quantities of researches have demonstrated silica nanoparticles (SiNPs) exposure
inevitably induced damage to respiratory system, nonetheless, knowledge of its toxicological …

The extensive application of silica nanoparticles (SiNPs) brings about inevitable
occupational, environmental, and even iatrogenic exposure for human beings. The liver …

Autophagy dysfunction is considered as a potential toxic mechanism of nanomaterials. Silica
nanoparticles (SiNPs) can induce autophagy, but the specific mechanism involved remains …

Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver-related morbidity and
mortality. Oxidative stress and release of pro-inflammatory cytokines, such as tumor necrosis …