[HTML][HTML] Tumor-infiltrating dendritic cell states are conserved across solid human cancers

GM Gerhard, R Bill, M Messemaker, AM Klein… - Journal of Experimental …, 2021 - rupress.org
Dendritic cells (DCs) contribute a small fraction of the tumor microenvironment but are
emerging as an essential antitumor component based on their ability to foster T cell …

Molecular mechanisms involved in dendritic cell dysfunction in cancer

M Tang, J Diao, MS Cattral - Cellular and Molecular Life Sciences, 2017 - Springer
Dendritic cells (DC) play a pivotal role in the tumor microenvironment (TME). As the primary
antigen-presenting cells in the tumor, DCs modulate anti-tumor responses by regulating the …

[HTML][HTML] Dendritic cells and cancer: from biology to therapeutic intervention

B Wylie, C Macri, JD Mintern, J Waithman - Cancers, 2019 - mdpi.com
Inducing effective anti-tumor immunity has become a major therapeutic strategy against
cancer. Dendritic cells (DC) are a heterogenous population of antigen presenting cells that …

The role of dendritic cells in cancer and anti-tumor immunity

AE Marciscano, N Anandasabapathy - Seminars in immunology, 2021 - Elsevier
Dendritic cells (DC) are key sentinels of the host immune response with an important role in
linking innate and adaptive immunity and maintaining tolerance. There is increasing …

[HTML][HTML] Dendritic cells in the cancer microenvironment

Y Ma, GV Shurin, Z Peiyuan, MR Shurin - Journal of Cancer, 2013 - ncbi.nlm.nih.gov
The complexity of the tumor immunoenvironment is underscored by the emergence and
discovery of different subsets of immune effectors and regulatory cells. Tumor-induced …

[HTML][HTML] Dendritic cell subsets in cancer immunity and tumor antigen sensing

A Del Prete, V Salvi, A Soriani, M Laffranchi… - Cellular & molecular …, 2023 - nature.com
Dendritic cells (DCs) exhibit a specialized antigen-presenting function and play crucial roles
in both innate and adaptive immune responses. Due to their ability to cross-present tumor …

Dendritic cells in cancer immunology and immunotherapy

SK Wculek, FJ Cueto, AM Mujal, I Melero… - Nature Reviews …, 2020 - nature.com
Dendritic cells (DCs) are a diverse group of specialized antigen-presenting cells with key
roles in the initiation and regulation of innate and adaptive immune responses. As such …

[HTML][HTML] Tumor-altered dendritic cell function: implications for anti-tumor immunity

KM Hargadon - Frontiers in immunology, 2013 - frontiersin.org
Dendritic cells (DC) are key regulators of both innate and adaptive immunity, and the array
of immunoregulatory functions exhibited by these cells is dictated by their differentiation …

Harnessing dendritic cells in cancer

L Apetoh, C Locher, F Ghiringhelli, G Kroemer… - Seminars in …, 2011 - Elsevier
Dendritic cells (DCs) are central to the initiation of tumor-specific immune responses.
However, the tumor microenvironment generates immunosuppressive cells and soluble …

Dendritic cells as shepherds of T cell immunity in cancer

MJ Pittet, M Di Pilato, C Garris, TR Mempel - Immunity, 2023 - cell.com
In cancer patients, dendritic cells (DCs) in tumor-draining lymph nodes can present antigens
to naive T cells in ways that break immunological tolerance. The clonally expanded progeny …