Generation and Characterization of recombinant SARS-CoV-2 expressing reporter genes

K Chiem, D Morales Vasquez, JG Park, RN Platt… - Journal of …, 2021 - Am Soc Microbiol
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
pathogen responsible for coronavirus disease 2019 (COVID-19), has devastated public …

A Bifluorescent-Based Assay for the Identification of Neutralizing Antibodies against SARS-CoV-2 Variants of Concern In Vitro and In Vivo

K Chiem, D Morales Vasquez, JA Silvas… - Journal of …, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged at the end of
2019 and has been responsible for the still ongoing coronavirus disease 2019 (COVID-19) …

Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses

C Ye, K Chiem, JG Park, JA Silvas… - Proceedings of the …, 2021 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the
current COVID-19 pandemic, is one of the biggest threats to public health. However, the …

An update on novel approaches for diagnosis and treatment of SARS-CoV-2 infection

A Safarchi, S Fatima, Z Ayati, F Vafaee - Cell & Bioscience, 2021 - Springer
The ongoing pandemic of coronavirus disease 2019 (COVID-19) has made a serious public
health and economic crisis worldwide which united global efforts to develop rapid, precise …

Construction of a noninfectious SARS-CoV-2 replicon for antiviral-drug testing and gene function studies

HT Nguyen, D Falzarano, V Gerdts, Q Liu - Journal of Virology, 2021 - Am Soc Microbiol
The emerging coronavirus disease 2019 (COVID-19) outbreak caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread worldwide, resulting …

Potent mouse monoclonal antibodies that block SARS-CoV-2 infection

Y Guo, A Kawaguchi, M Takeshita, T Sekiya… - Journal of Biological …, 2021 - ASBMB
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has developed into a global pandemic since its first outbreak …

Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing

X He, S Quan, M Xu, S Rodriguez… - Proceedings of the …, 2021 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) research and antiviral
discovery are hampered by the lack of a cell-based virus replication system that can be …

An infectious cDNA clone of SARS-CoV-2

X Xie, A Muruato, KG Lokugamage, K Narayanan… - Cell host & …, 2020 - cell.com
The ongoing pandemic of COVID-19, caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), underscores the urgency to develop experimental systems for …

[HTML][HTML] An optimized high-throughput SARS-CoV-2 dual reporter trans-complementation system for antiviral screening in vitro and in vivo

Y Li, X Tan, J Deng, X Liu, Q Liu, Z Zhang, X Huang… - Virologica Sinica, 2024 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still epidemic around
the world. The manipulation of SARS-CoV-2 is restricted to biosafety level 3 laboratories …

Monoclonal antibodies specific for SARS-CoV-2 spike protein suitable for multiple applications for current variants of concern

MS Morgan, K Yan, TT Le, RA Johnston, AA Amarilla… - Viruses, 2022 - mdpi.com
The global coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has spawned an ongoing demand for …